Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CCNK | O75909 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25028644 | 1.00 | AR (0.34) | ARDYRK1ANFATC1GSK3BCCNT1 | |
| SCHEMBL25028885 | 0.87 | AR (0.38) | ARDYRK1ANFATC1GSK3B | |
| SCHEMBL29364170 | 0.87 | AR (0.38) | ARDYRK1ANFATC1GSK3B | |
| SCHEMBL29361320 | 0.81 | AR (0.53) | ARDYRK1ANFATC1GSK3B | |
| SCHEMBL25027669 | 0.81 | AR (0.53) | ARDYRK1ANFATC1GSK3B | |
| SCHEMBL25027522 | 0.80 | DYRK1A (0.54) | ARDYRK1ANFATC1GSK3B | |
| SCHEMBL29364264 | 0.80 | DYRK1A (0.54) | ARDYRK1ANFATC1GSK3B | |
| SCHEMBL25029224 | 0.76 | DYRK1A (0.40) | ARDYRK1ANFATC1GSK3B | |
| SCHEMBL25029091 | 0.75 | AR (0.55) | AR | |
| SCHEMBL25027521 | 0.75 | AR (0.48) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |