⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799303 | 1.00 | — | — | |
| SCHEMBL9538730 | 0.78 | — | — | |
| SCHEMBL29909946 | 0.78 | — | — | |
| SCHEMBL611310 | 0.71 | CDC25B (0.35) | — | |
| SCHEMBL30605586 | 0.71 | CDC25B (0.35) | — | |
| SCHEMBL29476468 | 0.71 | CDC25B (0.35) | — | |
| SCHEMBL29903184 | 0.68 | — | — | |
| SCHEMBL29419946 | 0.68 | GSK3A (0.39) | — | |
| SCHEMBL23023244 | 0.65 | — | — | |
| SCHEMBL30118127 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120157686-A | Compound with AKT kinase degradation activity, preparation method and pharmaceutical application thereof | 南京正大天晴制药有限公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-119302960-A | Unit dose compositions of AKT inhibitors | 南京正大天晴制药有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-115916350-B | Unit dose compositions of AKT inhibitors | 南京正大天晴制药有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-115485276-B | Deuterated AKT kinase inhibitors | 南京正大天晴制药有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-117964620-A | AKT inhibitors | 南京正大天晴制药有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-115916350-A | Unit dose compositions of AKT inhibitors | 南京正大天晴制药有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115843298-A | Salt and crystal form of dihydropyrido [2,3-d ] pyrimidone derivative | 南京正大天晴制药有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-114907514-A | Multifunctional fiber and preparation method and application thereof | 北京洁尔爽高科技有限公司 | 2022-08-16 | — | — | CN | disclosed |
| WO-2022017448-A1 | SALT AND CRYSTAL FORM OF DIHYDROPYRIDO[2,3-D]PYRIMIDINE DERIVATE | 南京正大天晴制药有限公司 | 2022-01-27 | — | — | WO | disclosed |
| WO-2022017449-A1 | SALT OF DIHYDROPYRIDO[2,3-D]PYRIMIDINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 南京正大天晴制药有限公司 | 2022-01-27 | — | — | WO | disclosed |