SCHEMBL293624

SCHEMBL293624

O=[C]CNC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11884710 0.71
SCHEMBL10935145 0.71
SCHEMBL1759861 0.71
SCHEMBL1006431 0.71
SCHEMBL2428440 0.70
SCHEMBL2393601 0.69
SCHEMBL2386174 0.69
SCHEMBL10782655 0.67
SCHEMBL7634571 0.67
SCHEMBL17434288 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11226337-B2 Chemoproteomic profiling of protein electrophilic and oxidative post-translational modifications Zenagem, LLC (US) 2022-01-18 US claimed
US-20190204336-A1 CHEMOPROTEOMIC PROFILING OF PROTEIN ELECTROPHILIC AND OXIDATIVE POST-TRANSLATIONAL MODIFICATIONS Zenagem, LLC 2019-07-04 US claimed
EP-2643000-A2 THERAPEUTIC PIPERAZINES Dart Neuroscience (Cayman) Ltd (KY) 2013-10-02 EP claimed
WO-2012040258-A2 THERAPEUTIC PIPERAZINES HELICON THERAPEUTICS, INC. (US) 2012-03-29 WO claimed
US-20040063701-A1 Piperidine derivatives and anti-platelet agents containing the same AJINOMOTO CO., INC (JP) 2004-04-01 US claimed
EP-0976735-B1 PROCESS FOR PRODUCING PIPERIDINECARBOXYLIC ACID AMIDES AJINOMOTO KK (JP) 2003-10-29 EP claimed
US-20020147195-A1 Piperidine derivatives and anti-platelet agents containing the same AJINOMOTO CO., INC. (JP) 2002-10-10 US claimed
US-20020019533-A1 PIPERIDINE DERIVATIVES AND ANTI-PLATELET AGENTS CONTAINING THE SAME MAKINO SHINGO (JP) 2002-02-14 US claimed
EP-0682015-B1 Piperidine derivates and anti-platelet agents containing the same AJINOMOTO KK (JP) 2001-08-22 EP claimed
EP-1103544-A2 Piperidine derivatives and antiplatelet agents containing the same Ajinomoto Co., Inc. (JP) 2001-05-30 EP claimed
US-6207834-B1 REACTING 2-OXAZOLINE COMPOUND WITH A PIPERIDINE DERIVATIVE AJINOMOTO CO., INC. (JP) 2001-03-27 US claimed
EP-0976735-A1 PROCESS FOR PRODUCING PIPERIDINECARBOXYLIC ACID AMIDES Ajinomoto Co., Inc. (JP) 2000-02-02 EP claimed
EP-0653422-B1 Process for the preparation of 2-substituted 5-chlorimidazole-4-carbaldehydes LONZA AG (CH) 1998-02-25 EP claimed
US-5714501-A ANTIALLERGENIC/ANTIASTHMATIC AGENTS KOWA CO., LTD. (JP) 1998-02-03 US claimed
EP-0739881-A2 Piperidine derivatives KOWA CO. LTD. (JP) 1996-10-30 EP claimed
EP-0682015-A1 Piperidine derivates and anti-platelet agents containing the same Ajinomoto Co., Inc. (JP) 1995-11-15 EP claimed
EP-0173190-B1 PROCESS FOR THE PREPARATION OF 5-ACYL PYRIMIDINES BAYER AG (DE) 1991-09-11 EP claimed
US-4282211-A 1-Epi-2-deoxyfortimicin B and derivatives ABBOTT LABORATORIES (US) 1981-08-04 US claimed
JP-55055198-A None JP disclosed
US-4000122-A BACTERICIDES AMERICAN HOME PRODUCTS CORPORATION (US) 1976-12-28 US disclosed