Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.45 |
| ▸ | NFATC1 | O95644 | 2/20 | 0.45 |
| ▸ | CCNK | O75909 | 2/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | CDK7 | P50613 | 4/20 | 0.33 |
| ▸ | CCNH | P51946 | 4/20 | 0.33 |
| ▸ | MNAT1 | P51948 | 4/20 | 0.33 |
| ▸ | AR | P10275 | 3/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29364394 | 1.00 | GSK3B (0.45) | GSK3BDYRK1ANFATC1CCNKCDK12 | |
| SCHEMBL26180185 | 1.00 | GSK3B (0.45) | GSK3BDYRK1ANFATC1CCNKCDK12 | |
| SCHEMBL29363483 | 1.00 | GSK3B (0.45) | GSK3BDYRK1ANFATC1CCNKCDK12 | |
| SCHEMBL25029314 | 1.00 | GSK3B (0.45) | GSK3BDYRK1ANFATC1CCNKCDK12 | |
| SCHEMBL26180186 | 1.00 | GSK3B (0.45) | GSK3BDYRK1ANFATC1CCNKCDK12 | |
| SCHEMBL25027652 | 1.00 | GSK3B (0.45) | GSK3BDYRK1ANFATC1CCNKCDK12 | |
| SCHEMBL25029360 | 1.00 | GSK3B (0.45) | GSK3BDYRK1ANFATC1CCNKCDK12 | |
| SCHEMBL25028897 | 1.00 | GSK3B (0.45) | GSK3BDYRK1ANFATC1CCNKCDK12 | |
| SCHEMBL29361823 | 1.00 | GSK3B (0.45) | GSK3BDYRK1ANFATC1CCNKCDK12 | |
| SCHEMBL25028661 | 0.90 | GSK3B (0.48) | GSK3BDYRK1ANFATC1CCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |