Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 4/20 | 0.45 |
| ▸ | GSK3B | P49841 | 3/20 | 0.45 |
| ▸ | NFATC1 | O95644 | 2/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 8/20 | 0.40 |
| ▸ | CCNK | O75909 | 8/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.40 |
| ▸ | CDK2 | P24941 | 8/20 | 0.40 |
| ▸ | CDK9 | P50750 | 8/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 8/20 | 0.40 |
| ▸ | AR | P10275 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 5/20 | 0.33 |
| ▸ | CCNH | P51946 | 5/20 | 0.33 |
| ▸ | MNAT1 | P51948 | 4/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | CLK3 | P49761 | 1/20 | 0.31 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25028895 | 1.00 | DYRK1A (0.45) | DYRK1AGSK3BNFATC1CCNT1CCNK | |
| SCHEMBL25028901 | 1.00 | DYRK1A (0.45) | DYRK1AGSK3BNFATC1CCNT1CCNK | |
| SCHEMBL25028661 | 0.88 | GSK3B (0.48) | DYRK1AGSK3BNFATC1CCNT1CCNK | |
| SCHEMBL29364439 | 0.88 | GSK3B (0.48) | DYRK1AGSK3BNFATC1CCNT1CCNK | |
| SCHEMBL25028647 | 0.86 | DYRK1A (0.47) | DYRK1AGSK3BNFATC1CCNT1CCNK | |
| SCHEMBL29364406 | 0.86 | DYRK1A (0.47) | DYRK1AGSK3BNFATC1CCNT1CCNK | |
| SCHEMBL25029066 | 0.86 | DYRK1A (0.42) | DYRK1ACCNT1CCNKCCNE1CDK2 | |
| SCHEMBL25029249 | 0.83 | GSK3B (0.45) | DYRK1AGSK3BNFATC1CCNT1CCNK | |
| SCHEMBL25274305 | 0.83 | GSK3B (0.45) | DYRK1AGSK3BNFATC1CCNT1CCNK | |
| SCHEMBL25028646 | 0.83 | GSK3B (0.45) | DYRK1AGSK3BNFATC1CCNT1CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |