⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1521342 | 0.82 | KDM4E (0.37) | — | |
| SCHEMBL1521749 | 0.80 | KDM4E (0.36) | — | |
| SCHEMBL8194394 | 0.78 | — | — | |
| SCHEMBL6039559 | 0.76 | KDM4E (0.48) | — | |
| SCHEMBL293766 | 0.75 | — | — | |
| SCHEMBL10739303 | 0.73 | KDM4E (0.43) | — | |
| SCHEMBL3860595 | 0.73 | — | — | |
| SCHEMBL474814 | 0.73 | — | — | |
| SCHEMBL6988251 | 0.73 | — | — | |
| SCHEMBL1656918 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 432 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021143810-A1 | POLYPEPTIDE COMPOUND AND USE THEREOF | 珠海联邦制药股份有限公司 | 2021-07-22 | — | — | WO | claimed |
| CN-105566276-B | Benzo-hexatomic ring derivative as DPP-4 inhibitor and application thereof | 华东理工大学 | 2021-01-08 | — | — | CN | claimed |
| CN-112010835-A | Carbon-sulfur-containing dual-chiral sulfimide and sulfimide derivatives, and preparation and application thereof | 南开大学 | 2020-12-01 | — | — | CN | claimed |
| EP-3214079-B1 | SIX-MEMBERED RING BENZO DERIVATIVES AS DPP-4 INHIBITOR AND USE THEREOF | UNIV EAST CHINA SCIENCE & TECH (CN) | 2020-06-24 | — | — | EP | claimed |
| US-10479798-B2 | Six-membered ring benzo derivatives as DPP-4 inhibitor and use thereof | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-11-19 | — | — | US | claimed |
| WO-2017218580-A1 | SYNTHETIC METHODS FOR THE PREPARATION OF NICOTINAMIDE RIBOSIDE AND RELATED COMPOUNDS | REJUVENATION THERAPEUTICS CORPORATION (US) | 2017-12-21 | — | — | WO | claimed |
| US-20170313715-A1 | SIX-MEMBERED RING BENZO DERIVATIVES AS DPP-4 INHIBITOR AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2017-11-02 | — | — | US | claimed |
| EP-3214079-A1 | SIX-MEMBERED RING BENZO DERIVATIVES AS DPP-4 INHIBITOR AND USE THEREOF | East China University Of Science And Technology (CN) | 2017-09-06 | — | — | EP | claimed |
| US-9534014-B2 | Pharmaceutical compositions with attenuated release of phenolic opioids | SIGNATURE THERAPEUTICS, INC. (US) | 2017-01-03 | — | — | US | claimed |
| US-20150031635-A1 | Pharmaceutical Compositions with Attenuated Release of Phenolic Opioids | 3I, LP | 2015-01-29 | — | — | US | claimed |
| EP-0413209-A1 | LHRH analogs | TAP Pharmaceuticals Inc. (US) | 1991-02-20 | — | — | EP | claimed |
| EP-0400065-A1 | LHRH ANALOGS. | ABBOTT LAB (US) | 1990-12-05 | — | — | EP | claimed |
| EP-0375395-A2 | Derivatives of 3'-and 3\"-0-desmethyl avermectin compounds | MERCK & CO. INC. (US) | 1990-06-27 | — | — | EP | claimed |
| EP-0368175-A1 | 3S,7S-3-(Morpholinocarbonyl)-5-(2-chlorphenyl)-7,10-dimethyl-3,4-dihydro-2H,7H-cyclopenta[4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine. | BOEHRINGER INGELHEIM KG (DE) | 1990-05-16 | — | — | EP | claimed |
| WO-1989007450-A1 | LHRH ANALOGS | ABBOTT LABORATORIES (US) | 1989-08-24 | — | — | WO | claimed |
| EP-0328090-A2 | LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | claimed |
| EP-0077274-B1 | 3-AMINO-2-HYDROXY-4-PHENYLBUTANOIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1985-08-28 | — | — | EP | claimed |
| US-4474764-A | ANALGESICS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1984-10-02 | — | — | US | claimed |
| EP-0077274-A1 | 3-Amino-2-hydroxy-4-phenylbutanoic acid derivatives and pharmaceutical composition containing the same | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1983-04-20 | — | — | EP | claimed |
| US-4302584-A | FROM AN ACETAMIDO-ACETAL OR KETENE-ACETAL-AMINAL AND 3-METHYL-BUT-2-EN-1-OL | BASF AKTIENGESELLSCHAFT (DE) | 1981-11-24 | — | — | US | claimed |