Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 17/20 | 0.58 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2936597 | 1.00 | IGF1R (0.58) | IGF1RHCRTR1HCRTR2SMO | |
| Trifluoroacetic Acid SCHEMBL3727665 | 0.94 | IGF1R (0.52) | IGF1RHCRTR1HCRTR2SMO | |
| SCHEMBL2940768 | 0.89 | IGF1R (0.60) | IGF1RHCRTR1HCRTR2SMO | |
| SCHEMBL2941262 | 0.89 | IGF1R (0.60) | IGF1RHCRTR1HCRTR2SMO | |
| SCHEMBL2940771 | 0.89 | IGF1R (0.60) | IGF1RHCRTR1HCRTR2SMO | |
| SCHEMBL2942050 | 0.85 | IGF1R (0.44) | IGF1R | |
| SCHEMBL2942048 | 0.85 | IGF1R (0.44) | IGF1R | |
| Trifluoroacetic Acid SCHEMBL3734827 | 0.83 | IGF1R (0.54) | IGF1RHCRTR1HCRTR2SMO | |
| Trifluoroacetic Acid SCHEMBL3726606 | 0.83 | IGF1R (0.54) | IGF1RHCRTR1HCRTR2SMO | |
| SCHEMBL3002202 | 0.82 | IGF1R (0.52) | IGF1RSMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-B1 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2010-09-22 | — | — | EP | disclosed |