Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 8/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22589620 | 1.00 | DDR1 (0.44) | DDR1DHODHALPLTP53NPC1 | |
| SCHEMBL22589543 | 0.86 | DHODH (0.41) | DDR1DHODHALPLTP53NPC1 | |
| SCHEMBL29362936 | 0.86 | DHODH (0.41) | DDR1DHODHALPLTP53NPC1 | |
| SCHEMBL23269627 | 0.79 | TP53 (0.49) | DDR1TP53LMNASMN1; SMN2 | |
| SCHEMBL29254429 | 0.78 | DDR1 (0.41) | DDR1DHODHTP53NPC1RAB9A | |
| SCHEMBL22589457 | 0.78 | DHODH (0.43) | DDR1DHODHALPLTP53NPC1 | |
| SCHEMBL29365695 | 0.78 | DHODH (0.43) | DDR1DHODHALPLTP53NPC1 | |
| SCHEMBL22589505 | 0.77 | NR4A2 (0.45) | TP53NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL29362907 | 0.77 | NR4A2 (0.45) | TP53NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL22589454 | 0.76 | TP53 (0.46) | DDR1DHODHTP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119798159-A | PAPD5 inhibitors and methods of use thereof | 儿童医学中心公司 | 2025-04-11 | — | — | CN | disclosed |
| EP-3959197-A1 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2022-03-02 | — | — | EP | disclosed |
| CN-113993848-A | Inhibitors of PAPD5 and methods of use thereof | 儿童医学中心公司 | 2022-01-28 | — | — | CN | disclosed |