Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 18/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31336425 | 1.00 | NOTUM (0.50) | NOTUMPDE3BPDE3ACYP1A2PTGS1 | |
| SCHEMBL23826351 | 0.87 | NOTUM (0.53) | NOTUMCYP1A2 | |
| SCHEMBL23825794 | 0.81 | NOTUM (0.53) | NOTUMCYP1A2 | |
| SCHEMBL31336430 | 0.81 | NOTUM (0.47) | NOTUMCYP1A2 | |
| SCHEMBL28627451 | 0.81 | NOTUM (0.47) | NOTUMCYP1A2PTGS1 | |
| Hydrochloric Acid SCHEMBL23825826 | 0.81 | NOTUM (0.52) | NOTUMCYP1A2 | |
| SCHEMBL23825570 | 0.81 | NOTUM (0.52) | NOTUMCYP1A2 | |
| SCHEMBL23825825 | 0.81 | NOTUM (0.52) | NOTUMCYP1A2 | |
| SCHEMBL23825815 | 0.80 | NOTUM (0.54) | NOTUMCYP1A2 | |
| SCHEMBL23826601 | 0.80 | NOTUM (0.54) | NOTUMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220024921-A1 | 1,3,4-OXADIAZOLONE COMPOUND AND PHARMACEUTICAL | NIPPON SHINYAKU CO., LTD. (JP) | 2022-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220024921-A1 | 1,3,4-OXADIAZOLONE COMPOUND AND PHARMACEUTICAL | PIM1, PIM3, PIM2 | NOTUM 1103/4885PDE3B 27/4885PDE3A 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.