SCHEMBL2936693

SCHEMBL2936693

COC(=O)c1ccc2cc(C(=O)OC)c(S(=O)(=O)O)cc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.49
KDM4E B2RXH2 7/20 0.48
HSD17B10 Q99714 2/20 0.48
PTPN11 Q06124 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ALDH1A1 P00352 5/20 0.46
HPGD P15428 4/20 0.46
GAA P10253 3/20 0.46
MAPT P10636 2/20 0.46
GLA P06280 2/20 0.46
ATM Q13315 2/20 0.46
CASP1 P29466 1/20 0.46
CASP7 P55210 1/20 0.46
CYP19A1 P11511 1/20 0.43
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
TP53 P04637 1/20 0.43
POLB P06746 1/20 0.43
THRB P10828 1/20 0.43
CA1 P00915 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5994473 0.99 LCK (0.48) LCKKDM4EHSD17B10PTPN11SMN1; SMN2
SCHEMBL5994468 0.86 KDM4E (0.46) LCKKDM4EHSD17B10PTPN11SMN1; SMN2
SCHEMBL30151494 0.84 PTPN11 (0.58) LCKKDM4EHSD17B10PTPN11SMN1; SMN2
SCHEMBL3339517 0.83 KDM4E (0.58) KDM4EHSD17B10SMN1; SMN2ALDH1A1HPGD
SCHEMBL27397618 0.83 KDM4E (0.54) LCKKDM4EHSD17B10SMN1; SMN2ALDH1A1
Cesium SCHEMBL4605888 0.81 KDM4E (0.56) KDM4EHSD17B10SMN1; SMN2ALDH1A1HPGD
SCHEMBL1868219 0.81 KDM4E (0.56) KDM4EHSD17B10SMN1; SMN2ALDH1A1HPGD
SCHEMBL5597489 0.81 KDM4E (0.53) LCKKDM4EHSD17B10SMN1; SMN2ALDH1A1
SCHEMBL5597490 0.81 KDM4E (0.53) LCKKDM4EHSD17B10SMN1; SMN2ALDH1A1
SCHEMBL1863796 0.81 KDM4E (0.56) KDM4EHSD17B10SMN1; SMN2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1643019-B1 POLYETHER ESTER ELASTIC FIBER AND FABRICS AND CLOTHES MADE BY USING THE SAME TEIJIN FIBERS LTD (JP) 2010-09-22 EP disclosed
EP-1643019-A1 POLYETHER ESTER ELASTIC FIBER AND FABRICS AND CLOTHES MADE BY USING THE SAME Teijin Fibers Limited (JP) 2006-04-05 EP disclosed