SCHEMBL29366935

SCHEMBL29366935

CN1C(=O)c2sccc2N(C)c2nc(Nc3ccc(S(N)(=O)=O)cc3)ncc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STK4 Q13043 13/20 1.00
STK3 Q13188 5/20 1.00
AURKA O14965 4/20 1.00
PIK3CG P48736 4/20 1.00
AURKB Q96GD4 4/20 1.00
DCLK1 O15075 3/20 1.00
PIP5K1C O60331 1/20 1.00
ABL1 P00519 1/20 1.00
JAK1 P23458 1/20 1.00
TYK2 P29597 1/20 1.00
PIK3CA P42336 1/20 1.00
RIPK4 P57078 1/20 1.00
TAOK1 Q7L7X3 1/20 1.00
ULK2 Q8IYT8 1/20 1.00
PIP4K2C Q8TBX8 1/20 1.00
MAP3K3 Q99759 1/20 1.00
TAOK3 Q9H2K8 1/20 1.00
STK26 Q9P289 1/20 1.00
TAOK2 Q9UL54 1/20 1.00
MAP3K2 Q9Y2U5 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20609709 1.00 STK4 (1.00) STK4STK3AURKAPIK3CGAURKB
SCHEMBL20628565 0.91 STK3 (1.00) STK4STK3AURKAPIK3CGAURKB
SCHEMBL20628572 0.89 PIK3CG (0.79) STK4STK3AURKAPIK3CGAURKB
SCHEMBL20628500 0.88 PIK3CG (0.78) STK4STK3AURKAPIK3CGAURKB
SCHEMBL20628544 0.87 STK3 (0.81) STK4STK3AURKAPIK3CGAURKB
SCHEMBL20628488 0.86 STK3 (0.79) STK4STK3AURKAPIK3CGAURKB
SCHEMBL21938546 0.86 STK3 (0.76) STK4STK3AURKAPIK3CGAURKB
SCHEMBL20628550 0.85 STK3 (0.77) STK4STK3AURKAPIK3CGAURKB
SCHEMBL23219348 0.85 STK3 (0.77) STK4STK3AURKAPIK3CGAURKB
SCHEMBL20628393 0.85 STK3 (0.75) STK4STK3AURKAPIK3CGAURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121102232-B Application of YAP agonist in preparation of medicines for treating intestinal lymphatic dysfunction 吉林大学 2026-02-27 CN claimed
US-20250325551-A1 GASOTRANSMITTER METABOLITES AND ALZHEIMER'S DISEASE UNIV LOUISIANA STATE (US) 2025-10-23 US claimed
WO-2025093674-A2 METHOD FOR EXPANDING LIVER CELLS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2025-05-08 WO claimed
US-12280058-B2 Gasotransmitter metabolites and Alzheimer's disease BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2025-04-22 US claimed
US-12163156-B2 Cell induction method INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES (CN) 2024-12-10 US claimed
CN-118806769-A Application of mechanical signal perception related YAP (yaP pathway) modulator in preparation of anti-hepadnavirus drugs 复旦大学 2024-10-22 CN claimed
WO-2024109739-A1 THE HIPPO PATHWAY AS A PHARMACOLOGIC TARGET FOR TREATING REFRACTIVE DISORDERS Centre for Eye and Vision Research Limited (CN) 2024-05-30 WO claimed
CN-118006539-A Liver-specific biological ink, preparation method thereof and primary hepatocyte 3D biological printing model constructed based on same 宁波长都生物科技有限责任公司 2024-05-10 CN claimed
EP-4277978-A1 BLASTOCYST-LIKE CELL AGGREGATE AND METHODS IMBA-Institut für Molekulare Biotechnologie GmbH (AT) 2023-11-22 EP claimed
CN-116806258-A Blastocyst-like cell aggregates and methods IMBA-莫利库尔生物技术研究所 2023-09-26 CN claimed
CN-114366750-B Application of XMU-MP-1 in preparation of medicine for preventing and/or treating immune thrombocytopenia ITP 苏州大学 2022-11-25 CN claimed
CN-114807022-A Method for establishing cavernous fibrosis disease model 上海市第一人民医院 2022-07-29 CN claimed
WO-2022152774-A1 BLASTOCYST-LIKE CELL AGGREGATE AND METHODS IMBA - INSTITUT FÜR MOLEKULARE BIOTECHNOLOGIE GMBH (AT) 2022-07-21 WO claimed
US-20220220440-A1 METHODS FOR THE PRODUCTION OF HEPATOCYTES FUJIFILM Cellular Dynamics, Inc. (US) 2022-07-14 US claimed
CN-114149961-B Multi-lineage liver organoid and construction method and application thereof 天九再生医学(天津)科技有限公司 2022-04-22 CN claimed
CN-114366751-A XMU-MP-1 application in preparing medicine for treating osteoarthritis 西安市红会医院 2022-04-19 CN claimed
CN-114366750-A XMU-MP-1 application in preparing ITP medicine for preventing and/or treating immune thrombocytopenia 苏州大学 2022-04-19 CN claimed
EP-3966315-A1 METHODS FOR THE PRODUCTION OF HEPATOCYTES FUJIFILM Cellular Dynamics, Inc. (US) 2022-03-16 EP claimed
CN-114149961-A Multi-lineage liver organoid and construction method and application thereof 天九再生医学(天津)科技有限公司 2022-03-08 CN claimed
CN-113995842-A Application of Hippo signal channel blocker in preparation of medicine for resisting ER + breast tumor 新乡医学院 2022-02-01 CN claimed