Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.91 |
| ▸ | ACHE | P22303 | 1/20 | 0.91 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | APP | P05067 | 1/20 | 0.69 |
| ▸ | MAOA | P21397 | 1/20 | 0.68 |
| ▸ | MAOB | P27338 | 1/20 | 0.68 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | MET | P08581 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1842826 | 1.00 | TYR (0.91) | TYRACHEMAPTKDM4EALDH1A1 | |
| SCHEMBL31252895 | 1.00 | TYR (0.91) | TYRACHEMAPTKDM4EALDH1A1 | |
| SCHEMBL1917145 | 1.00 | TYR (0.91) | TYRACHEMAPTKDM4EALDH1A1 | |
| SCHEMBL29363766 | 1.00 | TYR (0.91) | TYRACHEMAPTKDM4EALDH1A1 | |
| SCHEMBL4812187 | 1.00 | TYR (0.91) | TYRACHEMAPTKDM4EALDH1A1 | |
| SCHEMBL17956819 | 0.96 | TYR (0.85) | TYRACHEMAPTKDM4EALDH1A1 | |
| SCHEMBL12299133 | 0.96 | TYR (0.85) | TYRACHEMAPTKDM4EALDH1A1 | |
| SCHEMBL17956820 | 0.96 | TYR (0.85) | TYRACHEMAPTKDM4EALDH1A1 | |
| N-Trans-Feruloyldopamine SCHEMBL31061232 | 0.95 | TYR (1.00) | TYRACHEMAPTKDM4EALDH1A1 | |
| N-Trans-Feruloyldopamine SCHEMBL1915822 | 0.95 | TYR (1.00) | TYRACHEMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114146104-A | Anti-inflammatory active extract of achyranthes aspera | 湖南时代阳光药业股份有限公司 | 2022-03-08 | — | — | CN | claimed |
| CN-110613741-B | Anti-inflammatory active extract of achyranthes aspera and preparation method thereof | 湖南时代阳光药业股份有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-114146104-A | Anti-inflammatory active extract of achyranthes aspera | 湖南时代阳光药业股份有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-114146104-A | Anti-inflammatory active extract of achyranthes aspera | 湖南时代阳光药业股份有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-110613741-B | Anti-inflammatory active extract of achyranthes aspera and preparation method thereof | 湖南时代阳光药业股份有限公司 | 2022-02-01 | — | — | CN | disclosed |