Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 6/20 | 0.65 |
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22559642 | 1.00 | KHK (0.65) | KHKIRAK4KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL22559630 | 0.99 | KHK (0.64) | KHKIRAK4KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL29368359 | 0.99 | KHK (0.64) | KHKIRAK4KMT2ANPC1RAB9A | |
| SCHEMBL22567077 | 0.88 | KHK (0.64) | KHKIRAK4KMT2ANPC1RAB9A | |
| SCHEMBL22126706 | 0.83 | KHK (0.61) | KHKIRAK4KMT2ANPC1RAB9A | |
| SCHEMBL23711747 | 0.82 | KHK (0.58) | KHKIRAK4KMT2ANPC1RAB9A | |
| SCHEMBL2548808 | 0.81 | KHK (0.56) | KHKKMT2ANPC1RAB9AKDM4E | |
| SCHEMBL30464135 | 0.81 | KHK (0.56) | KHKKMT2ANPC1RAB9AKDM4E | |
| SCHEMBL31279805 | 0.81 | KHK (0.74) | KHKIRAK4KMT2ANPC1RAB9A | |
| SCHEMBL23711713 | 0.81 | KHK (0.74) | KHKIRAK4KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3955914-A1 | NOVEL COMPOUNDS AND METHODS OF USE TREATING FRUCTOSE-RELATED DISORDERS OR DISEASES | Colorado Research Partners, LLC (US) | 2022-02-23 | — | — | EP | disclosed |
| CN-114007602-A | Novel compounds and methods of use for treating fructose-related disorders or diseases | 科罗拉多研究合作伙伴有限责任公司 | 2022-02-01 | — | — | CN | disclosed |