Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 12/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 12/20 | 0.44 |
| ▸ | GRAMD1A | Q96CP6 | 3/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22291550 | 1.00 | DDB1 (0.44) | DDB1CRBNGRAMD1AALKUSP30 | |
| SCHEMBL29367335 | 0.95 | CRBN (0.44) | DDB1CRBNALKUSP30GPR119 | |
| SCHEMBL22291497 | 0.95 | CRBN (0.44) | DDB1CRBNALKUSP30GPR119 | |
| SCHEMBL22291448 | 0.85 | CRBN (0.56) | DDB1CRBN | |
| SCHEMBL29367343 | 0.85 | CRBN (0.56) | DDB1CRBN | |
| SCHEMBL22291575 | 0.84 | CRBN (0.38) | DDB1CRBNGRAMD1AALKGPR119 | |
| SCHEMBL26524822 | 0.83 | CRBN (0.41) | DDB1CRBN | |
| SCHEMBL29045666 | 0.83 | CRBN (0.40) | DDB1CRBN | |
| SCHEMBL24299444 | 0.82 | CRBN (0.54) | DDB1CRBNGPR119 | |
| SCHEMBL22291602 | 0.82 | DDB1 (0.54) | DDB1CRBNGRAMD1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4188447-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2023-06-07 | — | — | EP | disclosed |
| WO-2022025880-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2022-02-03 | — | — | WO | disclosed |