SCHEMBL29370105

C[C@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	12/20	0.55

▸	NPY1R	P25929	7/20	0.55

▸	NPY5R	Q15761	7/20	0.55

▸	NPY2R	P49146	4/20	0.55

▸	OPRL1	P41146	2/20	0.48

▸	BACE1	P56817	1/20	0.48

▸	VIPR1	P32241	1/20	0.47

▸	VIPR2	P41587	1/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30632623	0.93	NPY4R (0.60)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL30799719	0.91	BACE1 (0.55)	NPY4RNPY1RNPY5RNPY2RBACE1
SCHEMBL29628209	0.91	NPY4R (0.52)	NPY4RNPY1RNPY5RNPY2ROPRL1
SCHEMBL30845381	0.91	NPY4R (0.59)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL30958098	0.91	NPY4R (0.59)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL30958097	0.91	NPY4R (0.59)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL29406322	0.91	NPY4R (0.59)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL4543180	0.91	NPY4R (0.64)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL7867783	0.90	NPY4R (0.53)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL7867797	0.90	NPY4R (0.53)	NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3554559-B1	METHOD FOR LABELING OF SENSITIVE AND THERMOSENSITIVE TARGETING BIOMOLECULES WITH TECHNETIUM BASED COMPOUNDS	BRACCO IMAGING SPA (IT)	2022-02-02	—	—	EP	disclosed