Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCR | P30988 | 4/20 | 0.67 |
| ▸ | NPY2R | P49146 | 10/20 | 0.61 |
| ▸ | NPY4R | P50391 | 8/20 | 0.61 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.61 |
| ▸ | NPY1R | P25929 | 8/20 | 0.61 |
| ▸ | EP300 | Q09472 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.59 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | GLP1R | P43220 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30938250 | 1.00 | CALCR (0.67) | CALCRNPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL29414492 | 1.00 | CALCR (0.68) | CALCRNPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL30938249 | 1.00 | CALCR (0.68) | CALCRNPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL30028547 | 0.97 | CALCR (0.65) | CALCRNPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL31507665 | 0.94 | CALCR (0.63) | CALCRNPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL30495665 | 0.91 | CALCR (0.65) | CALCRNPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL30887555 | 0.91 | CALCR (0.66) | CALCRNPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL30887977 | 0.90 | CALCR (0.64) | CALCRMAPK8MAPK9MAPK10KEAP1 | |
| SCHEMBL30495756 | 0.90 | CALCR (0.64) | CALCRNPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL30495633 | 0.90 | CALCR (0.62) | CALCRNPY2RNPY4RNPY5RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 386 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4713350-A2 | MUTATED AND WILD TYPE HUMANIN PROTEINS TO IMPROVE CAR-T OR TIL ADOPTIVE CELL THERAPY | H. Lee Moffitt Cancer Center and Research Institute, Inc. (US) | 2026-03-25 | — | — | EP | claimed |
| EP-4705287-A1 | SMALL MOLECULE HUMANIN MIMETICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-03-11 | — | — | EP | claimed |
| US-20250345391-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF SEPSIS | CHILDRENS HOSPITAL MED CT (US) | 2025-11-13 | — | — | US | claimed |
| US-12372538-B2 | Exosome assay for depression and psychosis and methods and agents for treating depression, psychosis and schizophrenia | GOETZL EDWARD J (US) | 2025-07-29 | — | — | US | claimed |
| CN-119677539-A | Combination therapy for modulating lipid production | 俄亥俄州创新基金会 | 2025-03-21 | — | — | CN | claimed |
| EP-4489865-A2 | COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION | Ohio State Innovation Foundation (US) | 2025-01-15 | — | — | EP | claimed |
| WO-2024243138-A2 | MUTATED AND WILD TYPE HUMANIN PROTEINS TO IMPROVE CAR-T OR TIL ADOPTIVE CELL THERAPY | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2024-11-28 | — | — | WO | claimed |
| WO-2024226731-A1 | SMALL MOLECULE HUMANIN MIMETICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-10-31 | — | — | WO | claimed |
| US-20240350587-A1 | SYSTEMS AND METHODS FOR DELIVERY OF HUMANIN OR OTHER PEPTIDES | TRANSDERMAL BIOTECHNOLOGY, INC. (US) | 2024-10-24 | — | — | US | claimed |
| US-12064467-B2 | Systems and methods for delivery of humanin or other peptides | TRANSDERMAL BIOTECHNOLOGY, INC. (US) | 2024-08-20 | — | — | US | claimed |
| US-20230228767-A1 | DETECTION OF SARS-COV-2 PROTEINS AND MITOCHONDRIAL PROTEINS IN PLASMA NEURON-DERIVED EXTRACELLULAR VESICLES AND ASTROCYTE-DERIVED EXTRACELLULAR VESICLES | GOETZL EDWARD J (US) | 2023-07-20 | — | — | US | claimed |
| CN-111107867-B | Composition for preventing alopecia or promoting hair growth comprising brain protecting agent | 济州大学校产学协力团 | 2023-07-04 | — | — | CN | claimed |
| CN-116376814-A | Application of Humanin in preparation for reducing sperm DNA fragment rate and improving semen quality | 昆明医科大学第一附属医院 | 2023-07-04 | — | — | CN | claimed |
| CN-115838412-A | New application of Humanin polypeptide analogue | 昆明医科大学第一附属医院 | 2023-03-24 | — | — | CN | claimed |
| CN-115651894-A | Application of HNG in preparation for promoting maturation of human oocyte | 昆明医科大学第一附属医院 | 2023-01-31 | — | — | CN | claimed |
| CN-115227805-A | Application of mitochondrial polypeptide Humanin and analogue in preparation of medicine for protecting ovarian function | 华中科技大学 | 2022-10-25 | — | — | CN | claimed |
| US-20220275038-A1 | CLSP DERIVATIVE INCAPABLE OF BEING AFFECTED BY CLSP INHIBITING SUBSTANCE, AND CLSP ACTIVITY ENHANCING/PROTECTING AGENT | TOKYO MEDICAL UNIVERSITY (JP) | 2022-09-01 | — | — | US | claimed |
| US-11401305-B2 | Nucleic acids encoding repetitive amino acid sequences rich in proline and alanine residues that have low repetitive nucleotide sequences | XL-PROTEIN GMBH (DE) | 2022-08-02 | — | — | US | claimed |
| US-20220128575-A1 | EXOSOME ASSAY FOR DEPRESSION AND PSYCHOSIS AND METHODS AND AGENTS FOR TREATING DEPRESSION, PSYCHOSIS AND SCHIZOPHRENIA | GOETZL EDWARD J (US) | 2022-04-28 | — | — | US | claimed |
| CN-114288387-A | Application of Humanin derivative HNG in preparation of heart failure treatment drugs | 重庆医科大学 | 2022-04-08 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240350587-A1 | SYSTEMS AND METHODS FOR DELIVERY OF HUMANIN OR OTHER PEPTIDES | MTPN, NLN, MFN2 | CALCR 4257/4885NPY2R 1335/4885NPY4R 1780/4885 |
| US-12064467-B2 | Systems and methods for delivery of humanin or other peptides | MTPN, NLN, MFN2 | CALCR 4257/4885NPY2R 1335/4885NPY4R 1780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.