SCHEMBL29373303

SCHEMBL29373303

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)O)C(C)C

nearest known ligand 0.65

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 10/20 0.65
▸ ECE1 P42892 1/20 0.65
▸ MUS81 Q96NY9 1/20 0.65
▸ RXFP1 Q9HBX9 1/20 0.63
▸ PTH1R Q03431 2/20 0.61
▸ KEAP1 Q14145 1/20 0.59
▸ NPBWR1 P48145 3/20 0.58
▸ SLC2A1 P11166 2/20 0.58
▸ OPRD1 P41143 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31087271 0.96 RXFP1 (0.68) GLP1RECE1MUS81RXFP1PTH1R
SCHEMBL30271994 0.96 RXFP1 (0.68) GLP1RECE1MUS81RXFP1PTH1R
SCHEMBL30076208 0.96 GLP1R (0.63) GLP1RECE1MUS81RXFP1PTH1R
SCHEMBL29462132 0.95 RXFP1 (0.70) GLP1RECE1MUS81RXFP1PTH1R
SCHEMBL30183270 0.95 RXFP1 (0.70) GLP1RECE1MUS81RXFP1PTH1R
SCHEMBL30049211 0.95 RXFP1 (0.66) GLP1RECE1MUS81RXFP1PTH1R
SCHEMBL31759108 0.94 RXFP1 (0.67) GLP1RECE1MUS81RXFP1PTH1R
SCHEMBL31453813 0.94 RXFP1 (0.70) GLP1RECE1MUS81RXFP1PTH1R
SCHEMBL30635326 0.93 RXFP1 (0.70) GLP1RECE1MUS81RXFP1PTH1R
SCHEMBL29848900 0.93 RXFP1 (0.67) GLP1RECE1MUS81RXFP1PTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3433267-B1 METHOD FOR PREPARING GLUCAGON-LIKE PEPTIDES BACHEM HOLDING AG (CH) 2022-08-24 — — EP claimed
US-20250188115-A1 PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2025-06-12 — — US disclosed
WO-2025078040-A1 LYSINE SALT AND METHOD OF MANUFACTURING A LYSINE DERIVATIVE BACHEM HOLDING AG (CH) 2025-04-17 — — WO disclosed
CN-116120427-B Semex lattice Synthesis method of lupeptide 浙江九洲药业股份有限公司 2024-12-10 — — CN disclosed
WO-2024159569-A1 METHOD FOR SYNTHESIZING SEMAGLUTIDE 浙江九洲药业股份有限公司 2024-08-08 — — WO disclosed
CN-117624332-A Preparation method of cable Ma Lutai 合肥科生景肽生物科技有限公司 2024-03-01 — — CN disclosed
CN-112912390-B GLP-1 analogues and methods of preparation 北京费森尤斯卡比医药有限公司 2023-12-15 — — CN disclosed
CN-116813693-B Label compound for polypeptide synthesis and application of label compound in polypeptide synthesis 苏州金顶生物有限公司 2023-12-01 — — CN disclosed
CN-117084971-A Liraglutide nasal administration in-situ temperature-sensitive gel preparation, and preparation method and application thereof 成都大学 2023-11-21 — — CN disclosed
CN-116836258-A Solid phase synthesis method of liraglutide 辽宁药联制药有限公司 2023-10-03 — — CN disclosed
EP-4217503-A1 A PROCESS FOR THE PREPARATION OF SEMAGLUTIDE AND SEMAPEPTIDE Dr. Reddy's Laboratories Limited (IN) 2023-08-02 — — EP disclosed
CN-116120427-A Synthesis method of semaglutin 浙江九洲药业股份有限公司 2023-05-16 — — CN disclosed
WO-2023279323-A1 METHOD FOR SYNTHESIZING GLP-1 ANALOG 深圳翰宇药业股份有限公司 2023-01-12 — — WO disclosed
WO-2022266927-A1 LIRAGLUTIDE VARIANT, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 深圳翰宇药业股份有限公司 2022-12-29 — — WO disclosed
CN-113024658-B Method for purifying liraglutide 翰宇药业(武汉)有限公司 2022-10-21 — — CN disclosed
EP-3433267-B1 METHOD FOR PREPARING GLUCAGON-LIKE PEPTIDES BACHEM HOLDING AG (CH) 2022-08-24 — — EP disclosed
US-11396533-B2 Process for the manufacture of GLP-1 analogues Fresenius Kabi Ipsum S.R.L. (IT) 2022-07-26 — — US disclosed
US-20220195004-A1 METHOD FOR PREPARING TARGET POLYPEPTIDE BY MEANS OF RECOMBINATION AND SERIES CONNECTION OF FUSED PROTEINS PEG-BIO BIOPHARM CO., LTD. (CHONGQING) (CN) 2022-06-23 — — US disclosed
WO-2022064517-A1 A PROCESS FOR THE PREPARATION OF SEMAGLUTIDE AND SEMAPEPTIDE DR. REDDY'S LABORATORIES LIMITED (IN) 2022-03-31 — — WO disclosed
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES Fresenius Kabi Ipsum S.R.L. (IT) 2022-02-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES GLP1R, IAPP, VIP GLP1R 1/4885ECE1 1243/4885MUS81 4016/4885
US-11396533-B2 Process for the manufacture of GLP-1 analogues GLP1R, IAPP, VIP GLP1R 1/4885ECE1 1243/4885MUS81 4016/4885
US-20250188115-A1 PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE GLP1R, IAPP, GCG GLP1R 1/4885ECE1 1694/4885MUS81 3775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback