Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.45 |
| ▸ | BRD4 | O60885 | 6/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1794967 | 0.94 | KDM1A (0.51) | KDM1ABRD4ALOX5APFEN1TRPV1 | |
| SCHEMBL12364471 | 0.93 | KDM1A (0.43) | KDM1ABRD4ALOX5APFEN1TRPV1 | |
| SCHEMBL1798976 | 0.88 | KDM1A (0.43) | KDM1ABRD4ALOX5APFEN1TRPV1 | |
| SCHEMBL12653110 | 0.88 | KDM1A (0.37) | KDM1ABRD4ALOX5APFEN1TRPV1 | |
| SCHEMBL1799974 | 0.87 | KDM1A (0.46) | KDM1ABRD4ALOX5APFEN1TRPV1 | |
| SCHEMBL12350194 | 0.87 | TRPV1 (0.52) | KDM1ABRD4ALOX5APFEN1TRPV1 | |
| SCHEMBL1798578 | 0.86 | KDM1A (0.50) | KDM1ABRD4ALOX5APFEN1TRPV1 | |
| SCHEMBL1796485 | 0.86 | TRPV1 (0.52) | KDM1ABRD4ALOX5APFEN1TRPV1 | |
| SCHEMBL1799834 | 0.84 | BRD4 (0.42) | KDM1ABRD4TRPV1CYP3A4 | |
| SCHEMBL1801347 | 0.83 | BRD4 (0.44) | KDM1ABRD4TRPV1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021330-B1 | BENZIMIDAZOLE MODULATORS OF VR1 | JANSSEN PHARMACEUTICA NV (BE) | 2010-09-22 | — | — | EP | claimed |