Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 18/20 | 0.52 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1344495 | 0.90 | AVPR2 (0.57) | AVPR2 | |
| SCHEMBL2935640 | 0.88 | AVPR2 (0.61) | AVPR2 | |
| SCHEMBL2939635 | 0.82 | AVPR2 (0.61) | AVPR2 | |
| SCHEMBL2931288 | 0.82 | AVPR2 (0.59) | AVPR2 | |
| SCHEMBL2938186 | 0.82 | AVPR2 (0.59) | AVPR2 | |
| SCHEMBL2939621 | 0.81 | AVPR2 (0.56) | AVPR2 | |
| SCHEMBL2935190 | 0.81 | AVPR2 (0.52) | AVPR2 | |
| SCHEMBL2936224 | 0.80 | AVPR2 (0.60) | AVPR2 | |
| SCHEMBL2937303 | 0.80 | AVPR2 (0.56) | AVPR2 | |
| SCHEMBL2931351 | 0.79 | AVPR2 (0.59) | AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778677-B1 | HETEROCYCLIC CONDENSED COMPOUNDS USEFUL AS ANTIDIURETIC AGENTS | VANTIA LTD (GB) | 2010-02-03 | — | — | EP | claimed |