Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.93 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16019318 | 1.00 | SMN1; SMN2 (0.93) | SMN1; SMN2KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL29618412 | 0.96 | SMN1; SMN2 (1.00) | SMN1; SMN2KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL5624979 | 0.96 | SMN1; SMN2 (1.00) | SMN1; SMN2KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL7913275 | 0.95 | SMN1; SMN2 (0.97) | SMN1; SMN2KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL23793117 | 0.79 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL16019317 | 0.79 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL30471680 | 0.79 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL30711985 | 0.78 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL845573 | 0.78 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL4426644 | 0.77 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112689633-B | For inhibiting Nav1.8 Pyridinecarboxamide Compounds | 利伯研究所公司 | 2025-01-24 | — | — | CN | disclosed |
| EP-4192816-A1 | COMPOUNDS AS C5AR INHIBITORS | Kira Pharmaceuticals (Suzhou) Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022028586-A1 | COMPOUNDS AS C5AR INHIBITORS | KIRA PHARMACEUTICALS (SUZHOU) LTD. (CN) | 2022-02-10 | — | — | WO | disclosed |