Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22465884 | 1.00 | ERN1 (0.50) | ERN1 | |
| SCHEMBL12767670 | 0.79 | ERN1 (0.61) | ERN1 | |
| SCHEMBL1165175 | 0.78 | ERN1 (0.35) | ERN1 | |
| SCHEMBL411743 | 0.75 | ERN1 (0.58) | ERN1 | |
| SCHEMBL29384703 | 0.75 | ERN1 (0.58) | ERN1 | |
| SCHEMBL22466223 | 0.75 | ERN1 (0.58) | ERN1 | |
| SCHEMBL30362870 | 0.74 | ERN1 (0.58) | ERN1 | |
| SCHEMBL7526965 | 0.72 | LOX (0.31) | — | |
| SCHEMBL20455582 | 0.71 | ERN1 (0.32) | ERN1 | |
| SCHEMBL19677742 | 0.70 | HDAC1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114025847-B | Compounds and compositions as modulators of TLR signaling | 神经孔疗法股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| EP-3946599-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING | Neuropore Therapies, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| CN-114025847-A | Compounds and compositions as modulators of TLR signaling | 神经孔疗法股份有限公司 | 2022-02-08 | — | — | CN | disclosed |