SCHEMBL29375862

SCHEMBL29375862

C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)CN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 9/20 0.62
▸ NPY5R Q15761 8/20 0.62
▸ NPY1R P25929 7/20 0.62
▸ NPY2R P49146 5/20 0.57
▸ OPRD1 P41143 7/20 0.55
▸ OPRM1 P35372 6/20 0.55
▸ OPRK1 P41145 1/20 0.55
▸ NPBWR1 P48145 1/20 0.53
▸ TFPI P10646 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29794248 0.93 NPY4R (0.56) NPY4RNPY5RNPY1RNPY2R
SCHEMBL29805234 0.92 QRFPR (0.58) NPY4RNPY5RNPY1RNPY2ROPRD1
SCHEMBL30820017 0.91 NPY4R (0.63) NPY4RNPY5RNPY1RNPY2R
SCHEMBL29794245 0.91 NPY4R (0.58) NPY4RNPY5RNPY1RNPY2R
SCHEMBL38660704 0.90 NPY5R (0.58) NPY4RNPY5RNPY1RNPY2ROPRD1
SCHEMBL29805279 0.89 QRFPR (0.60) NPY4RNPY5RNPY1RNPY2ROPRD1
SCHEMBL29805232 0.89 QRFPR (0.60) NPY4RNPY5RNPY1RNPY2ROPRD1
SCHEMBL31261768 0.88 NPY4R (0.57) NPY4RNPY5RNPY1RNPY2RTFPI
SCHEMBL29670861 0.88 QRFPR (0.54) NPY4RNPY5RNPY1RNPY2ROPRD1
SCHEMBL29679886 0.88 NPY5R (0.56) NPY4RNPY5RNPY1RNPY2ROPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12227563-B2 Anti-IGF-I receptor humanized antibody TEIJIN PHARMA LIMITED (JP) 2025-02-18 — — US disclosed
CN-110691794-B anti-IGF-I receptor antibodies 帝人制药株式会社 2023-10-27 — — CN disclosed
US-20230192868-A1 ANTI-IGF-I RECEPTOR ANTIBODY TEIJIN PHARMA LIMITED (JP) 2023-06-22 — — US disclosed
US-11629194-B2 Anti-IGF-I receptor antibodies, encoding nucleic acid molecules and methods of using said antibodies TEIJIN PHARMA LIMITED (JP) 2023-04-18 — — US disclosed
US-20220033485-A1 ANTI-IGF-I RECEPTOR HUMANIZED ANTIBODY TEIJIN PHARMA LIMITED (JP) 2022-02-03 — — US disclosed
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