SCHEMBL29376362

SCHEMBL29376362

CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](N)CO)C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.66
▸ GLP1R P43220 6/20 0.58
▸ BACE1 P56817 2/20 0.57
▸ BACE2 Q9Y5Z0 2/20 0.57
▸ VIPR1 P32241 1/20 0.56
▸ ECE1 P42892 1/20 0.55
▸ MUS81 Q96NY9 1/20 0.55
▸ NR3C1 P04150 2/20 0.54
▸ GCGR P47871 1/20 0.54
▸ GIPR P48546 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29373287 0.97 TFPI (0.66) TFPIGLP1RBACE1BACE2VIPR1
SCHEMBL30721576 0.94 TFPI (0.61) TFPI
SCHEMBL30861920 0.94 TFPI (0.65) TFPIGLP1RBACE1BACE2VIPR1
SCHEMBL29373682 0.94 TFPI (0.68) TFPIGLP1RBACE1BACE2VIPR1
SCHEMBL29375967 0.93 TFPI (0.59) TFPI
SCHEMBL30721553 0.93 TFPI (0.66) TFPIGLP1RBACE1BACE2VIPR1
SCHEMBL30429902 0.92 TFPI (0.68) TFPIGLP1RBACE1BACE2VIPR1
SCHEMBL31000935 0.92 TFPI (0.65) TFPIGLP1RVIPR1
SCHEMBL30836920 0.92 TFPI (0.66) TFPIGLP1RVIPR1ECE1MUS81
SCHEMBL29525489 0.91 TFPI (0.63) TFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3505533-B1 SYNTHESIS METHOD FOR LOW-RACEMIZATION IMPURITY LIRAGLUTIDE SHENZHEN JYMED TECH CO LTD (CN) 2025-01-15 — — EP claimed
US-11396533-B2 Process for the manufacture of GLP-1 analogues Fresenius Kabi Ipsum S.R.L. (IT) 2022-07-26 — — US claimed
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES Fresenius Kabi Ipsum S.R.L. (IT) 2022-02-10 — — US claimed
EP-3505533-B1 SYNTHESIS METHOD FOR LOW-RACEMIZATION IMPURITY LIRAGLUTIDE SHENZHEN JYMED TECH CO LTD (CN) 2025-01-15 — — EP disclosed
CN-112912390-B GLP-1 analogues and methods of preparation 北京费森尤斯卡比医药有限公司 2023-12-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES GLP1R, IAPP, VIP TFPI 525/4885GLP1R 1/4885BACE1 569/4885
US-11396533-B2 Process for the manufacture of GLP-1 analogues GLP1R, IAPP, VIP TFPI 525/4885GLP1R 1/4885BACE1 569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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