Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.57 |
| ▸ | KDM4A | O75164 | 3/20 | 0.57 |
| ▸ | PHF8 | Q9UPP1 | 9/20 | 0.57 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.53 |
| ▸ | KDM5A | P29375 | 4/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29373849 | 0.82 | PHF8 (0.59) | KDM4CKDM4APHF8KDM2BKDM5A | |
| SCHEMBL29376376 | 0.81 | KDM4C (0.57) | KDM4CKDM4APHF8KDM2BKDM5A | |
| SCHEMBL30589249 | 0.80 | KDM2B (0.58) | KDM4CKDM4APHF8KDM2BKDM5A | |
| SCHEMBL29376959 | 0.79 | PHF8 (0.57) | KDM4CKDM4APHF8KDM2BKDM5A | |
| SCHEMBL17604580 | 0.74 | KDM4C (0.67) | KDM4CKDM4APHF8KDM2BKDM5A | |
| SCHEMBL16034591 | 0.74 | PHF8 (0.68) | KDM4CKDM4APHF8KDM2BKDM5A | |
| SCHEMBL17604656 | 0.74 | KDM4C (0.69) | KDM4CKDM4APHF8KDM2BKDM5A | |
| SCHEMBL16034968 | 0.73 | KDM4C (1.00) | KDM4CKDM4APHF8KDM2BKDM5A | |
| SCHEMBL16034307 | 0.72 | KDM4C (1.00) | KDM4CKDM4APHF8KDM2BKDM5A | |
| SCHEMBL17604527 | 0.72 | KDM4C (0.72) | KDM4CKDM4APHF8KDM2BKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436445-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2023-09-06 | — | — | EP | disclosed |
| EP-3193881-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2022-02-09 | — | — | EP | disclosed |