⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2-Dimethoxybenzene SCHEMBL5308636 | 0.78 | CA1 (1.00) | — | |
| 1,2-Dimethoxybenzene SCHEMBL105872 | 0.78 | CA1 (1.00) | — | |
| 1,2-Dimethoxybenzene SCHEMBL29351917 | 0.78 | CA1 (1.00) | — | |
| SCHEMBL1802739 | 0.77 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL1803804 | 0.77 | CA1 (0.48) | — | |
| 1,2-Dimethoxybenzene SCHEMBL9793057 | 0.76 | CA1 (0.93) | — | |
| 1,2-Dimethoxybenzene SCHEMBL28602492 | 0.76 | CA1 (0.93) | — | |
| 1,2-Dimethoxybenzene SCHEMBL29229370 | 0.76 | CA1 (0.93) | — | |
| 1,2-Dimethoxybenzene SCHEMBL27996309 | 0.76 | CA1 (0.93) | — | |
| 1,2-Dimethoxybenzene SCHEMBL28052424 | 0.76 | CA1 (0.93) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 477 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192646-A1 | DIHYDRO-CYCLOPENTA-ISOQUINOLINE DERIVATIVES | UCB Biopharma SRL (BE) | 2023-06-22 | — | — | US | claimed |
| EP-4081299-A1 | DIHYDRO-CYCLOPENTA-ISOQUINOLINE DERIVATIVES | UCB Biopharma SRL (BE) | 2022-11-02 | — | — | EP | claimed |
| CN-112457363-B | Potato trisaccharide oleanolic acid saponin derivative and preparation method and application thereof | 华南农业大学 | 2021-12-24 | — | — | CN | claimed |
| WO-2021130255-A1 | DIHYDRO-CYCLOPENTA-ISOQUINOLINE DERIVATIVES | UCB Biopharma SRL (BE) | 2021-07-01 | — | — | WO | claimed |
| CN-112457363-A | Potato trisaccharide oleanolic acid saponin derivative and preparation method and application thereof | 华南农业大学 | 2021-03-09 | — | — | CN | claimed |
| CN-111196783-A | 2,4, 6-substituted pyrimidine derivatives containing acyl urea structure, and preparation method and application thereof | 郑州大学 | 2020-05-26 | — | — | CN | claimed |
| US-10647687-B2 | Spiropyrazine derivatives as inhibitors of non-apoptotic regulated cell-death | HELMHOLTZ ZENTRUM MÜNCHEN DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) | 2020-05-12 | — | — | US | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| CN-110590692-A | 6H-1, 3-oxazoline-6-ketone compound and application thereof in drugs for treating attention deficit hyperactivity disorder | 张振亭 | 2019-12-20 | — | — | CN | claimed |
| US-20180362475-A1 | SPIROPYRAZINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH | HELMHOLTZ ZENTRUM MÜNCHEN DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) | 2018-12-20 | — | — | US | claimed |
| EP-0881268-A1 | Fiber-reactive triphendioxazine dyes, process for their preparation and the use thereof | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 1998-12-02 | — | — | EP | claimed |
| EP-0863877-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1998-09-16 | — | — | EP | claimed |
| WO-1997016428-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1997-05-09 | — | — | WO | claimed |
| EP-0143461-B1 | RHODANINE DERIVATIVE, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 1989-09-06 | — | — | EP | claimed |
| EP-0315433-A2 | 3-amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants, muscle relaxants and anxiolytics | A.H. ROBINS COMPANY, INCORPORATED (US) | 1989-05-10 | — | — | EP | claimed |
| US-4606860-A | INHIBITS PLATLET AGGREGATION AND ALDOSE REDUCTOSE ACTIVITY | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1986-08-19 | — | — | US | claimed |
| EP-0143461-A2 | Rhodanine derivative, process for preparing the same and pharmaceutical composition containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1985-06-05 | — | — | EP | claimed |
| US-4455424-A | PIGMENTS AND DISPERSE DYES | SANDOZ LTD. (CH) | 1984-06-19 | — | — | US | claimed |
| EP-0087709-A1 | N,N',N\"-triaryl-1,2,3-triaminopropane derivatives, process for their preparation and their use as intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-09-07 | — | — | EP | claimed |
| US-4139530-A | CATIONIC DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-13 | — | — | US | claimed |