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SCHEMBL29376517

SCHEMBL29376517

CC(C)C[C@H](N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 19/20 0.64
▸ NPY1R P25929 12/20 0.64
▸ NPY5R Q15761 10/20 0.64
▸ NPY2R P49146 8/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31388270 0.94 NPY4R (0.64) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29376654 0.92 NPY4R (0.50) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31465103 0.91 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30341658 0.91 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31663446 0.91 NPY4R (0.56) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30966840 0.91 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31064805 0.91 NPY4R (0.50) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30661159 0.90 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30237703 0.90 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30974435 0.90 NPY4R (0.56) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4192853-A1 SOLUBLE NPY2 RECEPTOR AGONISTS Boehringer Ingelheim International GmbH (DE) 2023-06-14 — — EP claimed
CN-116171282-A Soluble NPY2 receptor agonists 勃林格殷格翰国际有限公司 2023-05-26 — — CN claimed
WO-2022029231-A1 SOLUBLE NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2022-02-10 — — WO claimed
EP-4192853-A1 SOLUBLE NPY2 RECEPTOR AGONISTS Boehringer Ingelheim International GmbH (DE) 2023-06-14 — — EP disclosed
CN-116171282-A Soluble NPY2 receptor agonists 勃林格殷格翰国际有限公司 2023-05-26 — — CN disclosed
WO-2022029231-A1 SOLUBLE NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2022-02-10 — — WO disclosed
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