Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 15/20 | 0.51 |
| ▸ | CTSD | P07339 | 3/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | BMP1 | P13497 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29725305 | 0.96 | DPP4 (0.49) | BACE1CTSDDPP4DPP8DPP9 | |
| SCHEMBL29777812 | 0.95 | DPP4 (0.50) | BACE1CTSDDPP4DPP8DPP9 | |
| SCHEMBL30462198 | 0.92 | DPP4 (0.52) | BACE1CTSDDPP4DPP8DPP9 | |
| SCHEMBL29777835 | 0.91 | BACE1 (0.53) | BACE1CTSDDPP4DPP8DPP9 | |
| SCHEMBL30575173 | 0.91 | DPP4 (0.43) | BACE1CTSDDPP4DPP8DPP9 | |
| SCHEMBL30479086 | 0.91 | BACE1 (0.53) | BACE1CTSDDPP4DPP8DPP9 | |
| SCHEMBL29978904 | 0.91 | DPP4 (0.49) | BACE1CTSDDPP4DPP8DPP9 | |
| SCHEMBL29777826 | 0.91 | BACE1 (0.53) | BACE1CTSDDPP4DPP8DPP9 | |
| SCHEMBL34464998 | 0.91 | DPP4 (0.51) | BACE1CTSDDPP4DPP8DPP9 | |
| SCHEMBL30712163 | 0.91 | DPP4 (0.54) | BACE1CTSDDPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220128556-A1 | METHODS OF DIAGNOSING DISEASE | 4D Pharma Cork Limited (IE) | 2022-04-28 | — | — | US | claimed |
| CN-114040986-A | Method of diagnosing disease | 4D制药科克有限公司 | 2022-02-11 | — | — | CN | claimed |
| EP-3947743-A1 | METHODS OF DIAGNOSING DISEASE | 4D Pharma Cork Limited (IE) | 2022-02-09 | — | — | EP | claimed |
| US-20220128556-A1 | METHODS OF DIAGNOSING DISEASE | 4D Pharma Cork Limited (IE) | 2022-04-28 | — | — | US | disclosed |
| CN-114040986-A | Method of diagnosing disease | 4D制药科克有限公司 | 2022-02-11 | — | — | CN | disclosed |
| EP-3947743-A1 | METHODS OF DIAGNOSING DISEASE | 4D Pharma Cork Limited (IE) | 2022-02-09 | — | — | EP | disclosed |