Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 5/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 5/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 5/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22466007 | 1.00 | KCNQ3 (0.40) | KCNQ3KCNQ2KLKB1RAB9ANPC1 | |
| SCHEMBL29375344 | 0.85 | KCNQ3 (0.43) | KCNQ3KCNQ2RAB9ASMN1; SMN2BACE1 | |
| SCHEMBL22465890 | 0.85 | KCNQ3 (0.43) | KCNQ3KCNQ2RAB9ASMN1; SMN2BACE1 | |
| SCHEMBL29377859 | 0.83 | KCNQ3 (0.48) | KCNQ3KCNQ2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29377323 | 0.81 | KCNQ3 (0.47) | KCNQ3KCNQ2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22465850 | 0.81 | KCNQ3 (0.47) | KCNQ3KCNQ2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22465932 | 0.79 | KCNQ3 (0.51) | KCNQ3KCNQ2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29377113 | 0.79 | KCNQ3 (0.51) | KCNQ3KCNQ2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22465914 | 0.78 | KCNQ3 (0.43) | KCNQ3KCNQ2RAB9ASMN1; SMN2BACE1 | |
| SCHEMBL29549562 | 0.78 | KCNQ3 (0.43) | KCNQ3KCNQ2RAB9ASMN1; SMN2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114025847-B | Compounds and compositions as modulators of TLR signaling | 神经孔疗法股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| EP-3946599-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING | Neuropore Therapies, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| CN-114025847-A | Compounds and compositions as modulators of TLR signaling | 神经孔疗法股份有限公司 | 2022-02-08 | — | — | CN | disclosed |