SCHEMBL29378201

SCHEMBL29378201

CCCCCCCCCCc1ccc(OC(F)(F)F)c(C=O)c1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.47
FAAH O00519 1/20 0.43
PPARG P37231 2/20 0.42
PPARA Q07869 2/20 0.42
S1PR2 O95136 1/20 0.39
S1PR4 O95977 1/20 0.39
S1PR1 P21453 1/20 0.39
S1PR3 Q99500 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26978594 1.00 CDK1 (0.47) CDK1FAAHPPARGPPARAS1PR2
SCHEMBL26110029 0.89 CHRM2 (0.37) CDK1
SCHEMBL30975320 0.83 CDK1 (0.47) CDK1FAAHPPARGPPARA
SCHEMBL31490070 0.83 CDK1 (0.44) CDK1FAAHPPARGPPARA
SCHEMBL29374627 0.82 CYP19A1 (0.43)
SCHEMBL26980591 0.82 CYP19A1 (0.43)
SCHEMBL28526539 0.82 CDK1 (0.54) CDK1PPARGPPARA
SCHEMBL7062043 0.82 CDK1 (0.41) CDK1FAAHPPARGPPARAS1PR2
SCHEMBL2541124 0.81 HTT (0.49) CDK1PPARGPPARA
SCHEMBL29377070 0.81 CYP19A1 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116472273-A Antidiabetic compounds and compositions 宁康瑞珠生物制药(珠海)有限公司 2023-07-21 CN disclosed
WO-2022028317-A1 ANTIDIABETIC COMPOUNDS AND COMPOSITIONS REZUBIO PHARMACEUTICALS CO., LTD (CN) 2022-02-10 WO disclosed