Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 20/20 | 0.67 |
| ▸ | MC5R | P33032 | 3/20 | 0.54 |
| ▸ | MC3R | P41968 | 3/20 | 0.54 |
| ▸ | MC1R | Q01726 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11891162 | 0.93 | MC4R (0.77) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891115 | 0.91 | MC4R (0.78) | MC4RMC5RMC3RMC1R | |
| Hydrochloric Acid SCHEMBL6072371 | 0.91 | MC4R (0.76) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891165 | 0.87 | MC4R (0.71) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891159 | 0.87 | MC4R (0.70) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891158 | 0.81 | MC4R (0.59) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891217 | 0.81 | MC4R (0.86) | MC4RMC5RMC3RMC1R | |
| SCHEMBL11891258 | 0.81 | MC4R (0.86) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13124244 | 0.80 | MC4R (0.78) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13124239 | 0.79 | MC4R (0.78) | MC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692114-B1 | NOVEL BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | IPSEN PHARMA (FR) | 2010-09-22 | — | — | EP | disclosed |
| EP-1692114-A1 | NOVEL BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005056533-A1 | NOVEL BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2005-06-23 | — | — | WO | disclosed |