SCHEMBL29378646

SCHEMBL29378646

CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCCN)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 12/20 0.51
NPY1R P25929 7/20 0.51
NPY2R P49146 5/20 0.51
NPY5R Q15761 5/20 0.51
GNAI3 P08754 1/20 0.43
GNAO1 P09471 1/20 0.43
GNAI1 P63096 1/20 0.43
FURIN P09958 3/20 0.40
NMT2 O60551 1/20 0.40
NMT1 P30419 1/20 0.40
SIRT6 Q8N6T7 1/20 0.40
SIRT1 Q96EB6 1/20 0.40
DPP8 Q6V1X1 1/20 0.38
DPP9 Q86TI2 1/20 0.38
DPP7 Q9UHL4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31376472 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RGNAI3
SCHEMBL30422560 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RGNAI3
SCHEMBL30121066 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RGNAI3
SCHEMBL8742594 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RGNAI3
SCHEMBL8742615 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RGNAI3
SCHEMBL30423395 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RGNAI3
SCHEMBL29642059 0.96 NPY4R (0.48) NPY4RNPY1RNPY2RNPY5RGNAI3
SCHEMBL10944182 0.95 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5RGNAI3
SCHEMBL10940273 0.95 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5RGNAI3
SCHEMBL10942024 0.95 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5RGNAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025227064-A1 GENOMIC EDITING METHODS TO TREAT CARDIOVASCULAR DISEASE, AND COMPOSITIONS FOR USE IN PRACTICING THE SAME RENASCI BIOTECHNOLOGIES, INC. (US) 2025-10-30 WO disclosed
WO-2024249770-A2 SPATIOTEMPORAL CONTROL OF GENOMICS AND EPIGENOMICS BY ULTRASOUND UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2024-12-05 WO disclosed
US-20220042040-A1 DUAL VECTOR SYSTEM FOR IMPROVED PRODUCTION OF PROTEINS IN ANIMAL CELLS UNIVERSITÄT FÜR BODENKULTUR WIEN (AT) 2022-02-10 US disclosed