Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 13/20 | 0.62 |
| ▸ | MME | P08473 | 1/20 | 0.58 |
| ▸ | ACE | P12821 | 1/20 | 0.58 |
| ▸ | CPA1 | P15085 | 1/20 | 0.58 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.58 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.56 |
| ▸ | CTSD | P07339 | 2/20 | 0.55 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29603718 | 1.00 | BACE1 (0.62) | BACE1MMEACECPA1ACE2 | |
| SCHEMBL29379622 | 1.00 | BACE1 (0.62) | BACE1MMEACECPA1ACE2 | |
| SCHEMBL30117298 | 0.93 | BACE1 (0.64) | BACE1MMEACECPA1ACE2 | |
| SCHEMBL30054652 | 0.92 | BACE1 (0.61) | BACE1BACE2CTSD | |
| SCHEMBL30819112 | 0.91 | BACE1 (0.56) | BACE1MMEACECPA1ACE2 | |
| SCHEMBL30054528 | 0.91 | BACE1 (0.56) | BACE1MMEACECPA1ACE2 | |
| SCHEMBL31220207 | 0.91 | BACE1 (0.58) | BACE1MMEACECPA1ACE2 | |
| SCHEMBL29350817 | 0.90 | BACE1 (0.66) | BACE1BACE2CTSD | |
| SCHEMBL30051590 | 0.90 | ACE (0.64) | BACE1MMEACECPA1ACE2 | |
| SCHEMBL29603617 | 0.89 | ACE (0.60) | BACE1MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220128556-A1 | METHODS OF DIAGNOSING DISEASE | 4D Pharma Cork Limited (IE) | 2022-04-28 | — | — | US | claimed |
| CN-114040986-A | Method of diagnosing disease | 4D制药科克有限公司 | 2022-02-11 | — | — | CN | claimed |
| EP-3947743-A1 | METHODS OF DIAGNOSING DISEASE | 4D Pharma Cork Limited (IE) | 2022-02-09 | — | — | EP | claimed |
| US-20220128556-A1 | METHODS OF DIAGNOSING DISEASE | 4D Pharma Cork Limited (IE) | 2022-04-28 | — | — | US | disclosed |
| CN-114040986-A | Method of diagnosing disease | 4D制药科克有限公司 | 2022-02-11 | — | — | CN | disclosed |
| EP-3947743-A1 | METHODS OF DIAGNOSING DISEASE | 4D Pharma Cork Limited (IE) | 2022-02-09 | — | — | EP | disclosed |