Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 3/20 | 0.45 |
| ▸ | REN | P00797 | 3/20 | 0.43 |
| ▸ | GUCY1A1 | Q02108 | 10/20 | 0.43 |
| ▸ | GUCY1B1 | Q02153 | 10/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23186742 | 1.00 | BUB1 (0.45) | BUB1RENGUCY1A1GUCY1B1ADORA3 | |
| SCHEMBL23186753 | 0.92 | BUB1 (0.47) | BUB1GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL29381976 | 0.92 | BUB1 (0.47) | BUB1GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL29381978 | 0.90 | BUB1 (0.45) | BUB1GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL23186747 | 0.90 | BUB1 (0.45) | BUB1GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL29382286 | 0.90 | BUB1 (0.45) | BUB1GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL23186756 | 0.90 | BUB1 (0.45) | BUB1GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL23186720 | 0.89 | BUB1 (0.45) | BUB1GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL23186745 | 0.89 | BUB1 (0.45) | BUB1GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL29379501 | 0.89 | BUB1 (0.45) | BUB1GUCY1A1GUCY1B1ADORA3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609883-B1 | FLUORINE-SUBSTITUTED INDAZOLE COMPOUNDS AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2022-06-29 | — | — | EP | disclosed |
| US-11242335-B2 | Fluorine-substituted indazole compounds and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11242335-B2 | Fluorine-substituted indazole compounds and uses thereof | GUCY1B2, GUCY1A2, PDE3A | BUB1 4073/4885REN 2272/4885GUCY1A1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.