Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29379542 | 0.88 | MAPT (0.51) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL22531220 | 0.88 | HDAC6 (0.44) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL29381106 | 0.87 | NPC1 (0.55) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL22531007 | 0.83 | HDAC6 (0.44) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL29379455 | 0.82 | HDAC6 (0.43) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL22531679 | 0.81 | HDAC4 (0.44) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL23013579 | 0.80 | HDAC6 (0.46) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL29381515 | 0.80 | HDAC6 (0.46) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL29381424 | 0.79 | HDAC4 (0.57) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL28860581 | 0.77 | HDAC6 (0.53) | HDAC6HDAC1HDAC8HDAC5HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3953353-A1 | NOVEL OXADIAZOLE COMPOUNDS FOR CONTROLLING OR PREVENTING PHYTOPATHOGENIC FUNGI | PI Industries Ltd. (IN) | 2022-02-16 | — | — | EP | claimed |
| EP-3953353-A1 | NOVEL OXADIAZOLE COMPOUNDS FOR CONTROLLING OR PREVENTING PHYTOPATHOGENIC FUNGI | PI Industries Ltd. (IN) | 2022-02-16 | — | — | EP | disclosed |