Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30420449 | 0.91 | EGFR (0.51) | EGFRERBB2KDREPHA2EPHB4 | |
| SCHEMBL25663391 | 0.91 | EGFR (0.51) | EGFRERBB2KDREPHA2EPHB4 | |
| SCHEMBL25663568 | 0.88 | EGFR (0.44) | EGFRERBB2KDREPHA2EPHB4 | |
| SCHEMBL29380757 | 0.88 | EGFR (0.44) | EGFRERBB2KDREPHA2EPHB4 | |
| SCHEMBL25663566 | 0.88 | EGFR (0.44) | EGFRERBB2KDREPHA2EPHB4 | |
| SCHEMBL29382657 | 0.88 | EGFR (0.43) | EGFRERBB2KDREPHA2EPHB4 | |
| SCHEMBL30429745 | 0.87 | EGFR (0.48) | EGFRERBB2EPHA2EPHB4 | |
| SCHEMBL25663542 | 0.87 | EGFR (0.48) | EGFRERBB2EPHA2EPHB4 | |
| SCHEMBL26055468 | 0.87 | EGFR (0.48) | EGFRERBB2EPHA2EPHB4 | |
| SCHEMBL25244341 | 0.86 | EGFR (0.51) | EGFRERBB2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022033410-A1 | EFGR INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海和誉生物医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |