SCHEMBL29384813

SCHEMBL29384813

CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)O)C(C)C

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 11/20 0.49
▸ SCTR P47872 1/20 0.49
▸ CALCR P30988 4/20 0.47
▸ CRHR1 P34998 1/20 0.47
▸ CRHR2 Q13324 1/20 0.47
▸ GCGR P47871 1/20 0.47
▸ GRPR P30550 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29387542 0.99 GLP1R (0.49) GLP1RSCTRCALCRCRHR1CRHR2
SCHEMBL30525424 0.95 GRPR (0.47) GLP1RSCTRCALCRCRHR1CRHR2
SCHEMBL30930541 0.89 GLP1R (0.54) GLP1RSCTRGCGR
SCHEMBL30974400 0.88 GLP1R (0.49) GLP1RSCTRGRPR
SCHEMBL30512529 0.87 GLP1R (0.48) GLP1RSCTRCALCRCRHR1CRHR2
SCHEMBL30436887 0.87 CALCR (0.55) GLP1RSCTRCALCRCRHR1CRHR2
SCHEMBL29680082 0.86 GLP1R (0.51) GLP1RSCTRCALCRCRHR1CRHR2
SCHEMBL29798786 0.86 GLP1R (0.46) GLP1RSCTRCALCRGCGRGRPR
SCHEMBL30262188 0.86 GLP1R (0.59) GLP1RSCTRGCGR
SCHEMBL30974246 0.85 BACE1 (0.47) GLP1RSCTRGRPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12364755-B2 Method for obtaining globally activated monocytes TRANSIMMUNE AG (DE) 2025-07-22 — — US disclosed
EP-3741843-B1 METHOD FOR OBTAINING IMMUNO-STIMULATORY DENDRITIC CELLS TRANSIMMUNE AG (DE) 2024-06-26 — — EP disclosed
US-20240093151-A1 DEVICE AND METHOD FOR OBTAINING IMMUNO-STIMULATORY ANTIGEN-PRESENTING CELLS YALE UNIVERSITY 2024-03-21 — — US disclosed
EP-3954377-B1 METHOD FOR OBTAINING GLOBALLY ACTIVATED MONOCYTES TRANSIMMUNE AG (DE) 2023-09-06 — — EP disclosed
EP-4159222-A1 DEVICE AND METHOD FOR OBTAINING IMMUNO-STIMULATORY ANTIGEN-PRESENTING CELLS Transimmune AG (DE) 2023-04-05 — — EP disclosed
EP-4067370-A1 HIGH PENETRATION PRODRUG COMPOSITIONS OF PEPTIDES AND PEPTIDE RELATED COMPOUNDS Yu, Chongxi (US) 2022-10-05 — — EP disclosed
US-20220280562-A1 METHOD FOR OBTAINING GLOBALLY ACTIVATED MONOCYTES TRANSIMMUNE AG (DE) 2022-09-08 — — US disclosed
EP-3316896-B1 DEVICE AND METHOD FOR OBTAINING IMMUNO-STIMULATORY ANTIGEN-PRESENTING CELLS TRANSIMMUNE AG (DE) 2022-09-07 — — EP disclosed
US-20220259556-A1 METHOD FOR OBTAINING IMMUNO-SUPPRESSIVE DENDRITIC CELLS TRANSIMMUNE AG (DE) 2022-08-18 — — US disclosed
CN-114410581-A Method for obtaining immunosuppressive dendritic cells 特兰西穆内有限公司 2022-04-29 — — CN disclosed
CN-106604988-B Method for obtaining globally activated monocytes 特兰西穆内有限公司 2022-04-19 — — CN disclosed
US-20220112462-A1 METHOD FOR OBTAINING IMMUNO-STIMULATORY DENDRITIC CELLS TRANSIMMUNE AG (DE) 2022-04-14 — — US disclosed
EP-3954377-A1 METHOD FOR OBTAINING GLOBALLY ACTIVATED MONOCYTES Transimmune AG (DE) 2022-02-16 — — EP disclosed
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