Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 20/20 | 0.79 |
| ▸ | CHD1 | O14646 | 2/20 | 0.79 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.69 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.69 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25204677 | 1.00 | EHMT2 (0.79) | EHMT2CHD1ADRA1DEZH2EHMT1 | |
| SCHEMBL25231361 | 0.99 | EHMT2 (0.81) | EHMT2CHD1ADRA1DEZH2EHMT1 | |
| SCHEMBL29384861 | 0.99 | EHMT2 (0.81) | EHMT2CHD1ADRA1DEZH2EHMT1 | |
| SCHEMBL25239670 | 0.98 | EHMT2 (0.80) | EHMT2CHD1ADRA1DEZH2EHMT1 | |
| SCHEMBL29382526 | 0.97 | EHMT2 (0.85) | EHMT2CHD1ADRA1DEZH2EHMT1 | |
| SCHEMBL25201967 | 0.97 | EHMT2 (0.85) | EHMT2CHD1ADRA1DEZH2EHMT1 | |
| SCHEMBL29382797 | 0.95 | EHMT2 (0.83) | EHMT2CHD1EHMT1 | |
| SCHEMBL25229558 | 0.95 | EHMT2 (0.83) | EHMT2CHD1EHMT1 | |
| SCHEMBL25235013 | 0.94 | EHMT2 (0.88) | EHMT2CHD1EHMT1 | |
| SCHEMBL29382706 | 0.94 | EHMT2 (0.88) | EHMT2CHD1EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192826-A1 | SMALL MOLECULES FOR THE TREATMENT OF AUTOIMMUNE DISEASES AND CANCER | Athos Therapeutics, Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022031939-A1 | SMALL MOLECULES FOR THE TREATMENT OF AUTOIMMUNE DISEASES AND CANCER | ATHOS THERAPEUTICS, INC. (US) | 2022-02-10 | — | — | WO | disclosed |