Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376321 | 0.82 | NAMPT (0.48) | MEN1KMT2APTPN1MAPK1HDAC8 | |
| SCHEMBL12013723 | 0.82 | NAMPT (0.48) | MEN1KMT2APTPN1MAPK1HDAC8 | |
| SCHEMBL14138611 | 0.82 | NAMPT (0.48) | MEN1KMT2APTPN1MAPK1HDAC8 | |
| SCHEMBL23794828 | 0.81 | NR1H2 (0.39) | MEN1KMT2APTPN1NR1H2MAPK1 | |
| SCHEMBL26260560 | 0.81 | NR1H2 (0.39) | MEN1KMT2APTPN1NR1H2MAPK1 | |
| SCHEMBL29384815 | 0.80 | MEN1 (0.39) | MEN1KMT2APTPN1NR1H2MAPK1 | |
| SCHEMBL23868269 | 0.80 | MEN1 (0.39) | MEN1KMT2APTPN1NR1H2MAPK1 | |
| SCHEMBL23868265 | 0.80 | MEN1 (0.39) | MEN1KMT2APTPN1NR1H2MAPK1 | |
| SCHEMBL34469262 | 0.77 | MEN1 (0.41) | MEN1KMT2APTPN1NR1H2SETD7 | |
| SCHEMBL18435512 | 0.77 | ESR2 (0.59) | MEN1KMT2APTPN1NR1H2ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057739-A | Diazepinone derivatives and their use in the treatment of hepatitis b infections | 诺维拉治疗公司 | 2022-02-18 | — | — | CN | disclosed |