Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.76 |
| ▸ | HPGD | P15428 | 11/20 | 0.76 |
| ▸ | HTT | P42858 | 3/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.76 |
| ▸ | POLB | P06746 | 2/20 | 0.76 |
| ▸ | NPY1R | P25929 | 1/20 | 0.76 |
| ▸ | NPY2R | P49146 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12236578 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1HPGDHTTMAPT | |
| SCHEMBL29565837 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1HPGDHTTMAPT | |
| SCHEMBL12236577 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1HPGDHTTMAPT | |
| SCHEMBL27932466 | 0.83 | KDM4E (1.00) | KDM4EALDH1A1HPGDHTTMAPT | |
| SCHEMBL14864212 | 0.82 | KDM4E (0.85) | KDM4EALDH1A1HPGDHTTMAPT | |
| SCHEMBL12259166 | 0.82 | KDM4E (0.85) | KDM4EALDH1A1HPGDHTTMAPT | |
| SCHEMBL12236584 | 0.82 | KDM4E (0.85) | KDM4EALDH1A1HPGDHTTMAPT | |
| SCHEMBL12236575 | 0.81 | KDM4E (0.84) | KDM4EALDH1A1HPGDHTTMAPT | |
| SCHEMBL12236582 | 0.81 | KDM4E (0.84) | KDM4EALDH1A1HPGDHTTMAPT | |
| SCHEMBL29934340 | 0.79 | KDM4E (0.80) | KDM4EALDH1A1HPGDHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112014494-B | Method for separating eggliflozin and isomer thereof | 上海柏狮生物科技有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-111566112-B | Crystal form of eggliflozin and preparation method thereof | 广东东阳光药业有限公司 | 2022-02-15 | — | — | CN | disclosed |