Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333138 | 1.00 | CYP3A4 (0.68) | CYP3A4CYP2C9CYP2C19KDM4EMAPT | |
| SCHEMBL6693749 | 0.98 | CYP3A4 (0.70) | CYP3A4CYP2C9CYP2C19KDM4EMAPT | |
| SCHEMBL31026506 | 0.93 | CYP3A4 (0.67) | CYP3A4CYP2C9CYP2C19KDM4EMAPT | |
| SCHEMBL7833889 | 0.93 | CYP3A4 (0.67) | CYP3A4CYP2C9CYP2C19KDM4EMAPT | |
| SCHEMBL6371432 | 0.87 | KCNH2 (0.58) | CYP3A4CYP2C9CYP2C19KDM4EMAPT | |
| SCHEMBL29984901 | 0.85 | CYP3A4 (0.61) | CYP3A4CYP2C9CYP2C19KDM4EMAPT | |
| SCHEMBL550215 | 0.85 | CYP3A4 (0.61) | CYP3A4CYP2C9CYP2C19KDM4EMAPT | |
| SCHEMBL12849677 | 0.81 | CYP3A4 (1.00) | CYP3A4CYP2C9CYP2C19KDM4EMAPT | |
| SCHEMBL30947333 | 0.80 | CYP3A4 (0.69) | CYP3A4CYP2C9CYP2C19KDM4EMAPT | |
| SCHEMBL10740501 | 0.80 | CYP3A4 (0.48) | CYP3A4CYP2C9CYP2C19KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057623-A | N-naphthyl indole derivative and synthetic method thereof | 湖南第一师范学院 | 2022-02-18 | — | — | CN | claimed |
| CN-114031613-A | 1- (benzo [ b ] thiophene-7-yl) -indole derivative and synthetic method thereof | 湖南第一师范学院 | 2022-02-11 | — | — | CN | claimed |
| CN-119264028-A | 1-Trifluoromethylthio-indole Synthesis method of indole compound | 江南大学 | 2025-01-07 | — | — | CN | disclosed |
| CN-114057623-B | N-naphthyl indole derivative and synthesis method thereof | 湖南第一师范学院 | 2023-07-21 | — | — | CN | disclosed |
| CN-114057623-A | N-naphthyl indole derivative and synthetic method thereof | 湖南第一师范学院 | 2022-02-18 | — | — | CN | disclosed |
| CN-114031613-A | 1- (benzo [ b ] thiophene-7-yl) -indole derivative and synthetic method thereof | 湖南第一师范学院 | 2022-02-11 | — | — | CN | disclosed |