SCHEMBL2938699

SCHEMBL2938699

Cc1nc(N)nc2[nH]cnc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 2/20 0.37
GDA Q9Y2T3 1/20 0.37
MAP3K5 Q99683 1/20 0.36
CDK2 P24941 3/20 0.35
DPP4 P27487 1/20 0.35
DHFR P00374 6/20 0.35
PIK3CA P42336 1/20 0.34
ALDH1A1 P00352 3/20 0.33
CDK1 P06493 2/20 0.33
CCNB1 P14635 2/20 0.33
CCNA2 P20248 2/20 0.33
CCNA1 P78396 2/20 0.33
MGMT P16455 1/20 0.33
CYP1A2 P05177 1/20 0.33
HPGD P15428 1/20 0.33
NUDT1 P36639 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
PIN1 Q13526 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7019371 0.79 PDPK1 (0.36) PDPK1ALDH1A1HPGDHSD17B10KDM4E
2,6-Diaminopurine SCHEMBL24052 0.79 GDA (0.48) PDPK1GDAMAP3K5CDK2DPP4
2,6-Diaminopurine SCHEMBL29444619 0.79 GDA (0.48) PDPK1GDAMAP3K5CDK2DPP4
SCHEMBL28384784 0.78 PDPK1 (0.36) PDPK1GDAMAP3K5CDK2DPP4
Ammonia Solution, Strong SCHEMBL16871771 0.78 PDPK1 (0.35) PDPK1ALDH1A1HPGDHSD17B10KDM4E
2,6-Diaminopurine SCHEMBL8757968 0.78 GDA (0.47) PDPK1GDAMAP3K5CDK2DPP4
2,6-Diaminopurine SCHEMBL6423146 0.78 GDA (0.47) PDPK1GDAMAP3K5CDK2DPP4
SCHEMBL129817 0.77 CHUK (0.44) PDPK1GDAMAP3K5CDK2DPP4
SCHEMBL10579996 0.77 PDPK1 (0.35) PDPK1GDAMAP3K5CDK2DPP4
Thioguanine SCHEMBL218891 0.76 PDPK1 (0.37) PDPK1GDAMAP3K5CDK2DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1454 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634380-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-10-22 EP claimed
WO-2025137275-A1 NOVEL CAS NUCLEASES AND POLYNUCLEOTIDES ENCODING THE SAME MODERNATX, INC. (US) 2025-06-26 WO claimed
EP-4565692-A2 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-06-11 EP claimed
WO-2024129779-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION MODERNATX, INC. (US) 2024-06-20 WO claimed
WO-2024031087-A2 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION MODERNATX, INC. (US) 2024-02-08 WO claimed
WO-2023215498-A2 COMPOSITIONS AND METHODS FOR CD28 ANTAGONISM MODERNATX, INC. (US) 2023-11-09 WO claimed
CN-104918939-B Purine inhibitors of human phosphatidylinositol 3-kinase 默沙东公司 2018-08-28 CN claimed
US-5817799-A 2'-Fluorofuranosyl derivatives and methods for preparing 2'-fluoropyrimidine and 2'-fluoropurine nucleosides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1998-10-06 US claimed
US-5563049-A 2',3'-dideoxy purine nucleosides and process for the preparation thereof NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-10-08 US claimed
EP-0540686-B1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1995-08-30 EP claimed
EP-0540686-A4 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1993-05-26 EP claimed
EP-0540686-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES. US COMMERCE (US) 1993-05-12 EP claimed
WO-1992001700-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1992-02-06 WO claimed
JP-58057395-A None JP disclosed
JP-58059998-A None JP disclosed
JP-58057396-A None JP disclosed
EP-0839813-A1 9-(2-DEOXY-2-FLUORO-4-THIO-BETA-D-ARABINOFURANOSYL)PURINE DERIVATIVES YAMASA CORPORATION (JP) 1998-05-06 EP disclosed
JP-S5859998-A PREPARATION OF 2-FLUORO-6-METHYLPURINE NUCLEOSIDE YAMASA SHOYU CO LTD 1983-04-09 JP disclosed
JP-S5857395-A 2-AMINO-6-ALKOXYCARBONYLMETHYLPURINE NUCLEOSIDE YAMASA SHOYU CO LTD 1983-04-05 JP disclosed
JP-S5857396-A 2-HYDROXY-6-METHYLPURINE NUCLEOSIDE YAMASA SHOYU CO LTD 1983-04-05 JP disclosed