Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.64 |
| ▸ | TERT | O14746 | 2/20 | 0.61 |
| ▸ | DTYMK | P23919 | 4/20 | 0.60 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.53 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.53 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RNASEL | Q05823 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29423008 | 1.00 | F2 (0.64) | F2TERTDTYMKP2RY2P2RY4 | |
| SCHEMBL29395274 | 1.00 | F2 (0.64) | F2TERTDTYMKP2RY2P2RY4 | |
| SCHEMBL29959672 | 1.00 | F2 (0.64) | F2TERTDTYMKP2RY2P2RY4 | |
| SCHEMBL29689844 | 1.00 | F2 (0.64) | F2TERTDTYMKP2RY2P2RY4 | |
| SCHEMBL29716657 | 1.00 | F2 (0.64) | F2TERTDTYMKP2RY2P2RY4 | |
| SCHEMBL32665846 | 1.00 | F2 (0.64) | F2TERTDTYMKP2RY2P2RY4 | |
| SCHEMBL29986652 | 1.00 | F2 (0.64) | F2TERTDTYMKP2RY2P2RY4 | |
| SCHEMBL14174120 | 1.00 | F2 (0.64) | F2TERTDTYMKP2RY2P2RY4 | |
| SCHEMBL29690373 | 1.00 | F2 (0.64) | F2TERTDTYMKP2RY2P2RY4 | |
| SCHEMBL14184947 | 1.00 | F2 (0.64) | F2TERTDTYMKP2RY2P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4208173-A1 | METHODS OF PREPARING PROTEIN-OLIGONUCLEOTIDE COMPLEXES | Dyne Therapeutics, Inc. (US) | 2023-07-12 | — | — | EP | disclosed |
| US-20220211813-A1 | METHODS FOR TREATMENT OF NIEMANN-PICK DISEASE TYPE C | LOMA LINDA UNIVERSITY (US) | 2022-07-07 | — | — | US | disclosed |
| WO-2022051665-A1 | METHODS OF PREPARING PROTEIN-OLIGONUCLEOTIDE COMPLEXES | DYNE THERAPEUTICS, INC. (US) | 2022-03-10 | — | — | WO | disclosed |
| EP-3952859-A1 | METHODS FOR TREATMENT OF NIEMANN-PICK DISEASE TYPE C | Loma Linda University (US) | 2022-02-16 | — | — | EP | disclosed |