Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 14/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 13/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 13/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dotefonium SCHEMBL2733352 | 0.99 | CHRM3 (0.41) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL14408517 | 0.68 | CHRM3 (0.48) | CHRM3CHRM2CHRM1ALDH1A1POLB | |
| SCHEMBL4620168 | 0.68 | CHRM3 (0.41) | CHRM3CHRM2CHRM1CHRM4ALDH1A1 | |
| SCHEMBL5964331 | 0.68 | CHRM3 (0.50) | CHRM3CHRM2CHRM1ALDH1A1POLB | |
| SCHEMBL73656 | 0.68 | CHRM3 (0.50) | CHRM3CHRM2CHRM1ALDH1A1POLB | |
| SCHEMBL11284831 | 0.68 | CHRM3 (0.50) | CHRM3CHRM2CHRM1ALDH1A1POLB | |
| SCHEMBL74291 | 0.67 | CHRM3 (0.49) | CHRM3CHRM2CHRM1ALDH1A1POLB | |
| Etipirium SCHEMBL29388403 | 0.66 | CHRM2 (0.69) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Etipirium SCHEMBL916033 | 0.65 | CHRM2 (0.67) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL28905886 | 0.65 | CHRM3 (0.54) | CHRM3CHRM2CHRM1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220047505-A1 | Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration | STI PHARMA, LLC (US) | 2022-02-17 | — | — | US | disclosed |