Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 14/20 | 0.54 |
| ▸ | NTRK3 | Q16288 | 4/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 4/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28690954 | 1.00 | NTRK1 (0.54) | NTRK1NTRK3NTRK2EGFRERBB2 | |
| SCHEMBL28697267 | 0.92 | NTRK1 (0.64) | NTRK1NTRK3NTRK2 | |
| SCHEMBL28698672 | 0.91 | NTRK1 (0.53) | NTRK1NTRK3NTRK2 | |
| SCHEMBL28700935 | 0.90 | NTRK1 (0.47) | NTRK1NTRK3NTRK2CDK2 | |
| SCHEMBL29390713 | 0.89 | NTRK1 (0.50) | NTRK1NTRK3NTRK2 | |
| SCHEMBL28700924 | 0.89 | NTRK1 (0.50) | NTRK1NTRK3NTRK2 | |
| SCHEMBL29387485 | 0.87 | NTRK1 (0.51) | NTRK1NTRK3NTRK2 | |
| SCHEMBL29387516 | 0.87 | NTRK1 (0.43) | NTRK1NTRK3NTRK2CDK1CDK4 | |
| SCHEMBL29390863 | 0.87 | NTRK1 (0.43) | NTRK1CDK1CDK4CDK2 | |
| SCHEMBL28707109 | 0.87 | NTRK1 (0.46) | NTRK1NTRK3NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072387-B | Indazole compound, pharmaceutical composition and application thereof | 暨南大学 | 2024-03-08 | — | — | CN | disclosed |
| CN-114072387-A | Indazole compound and medicinal composition and application thereof | 暨南大学 | 2022-02-18 | — | — | CN | disclosed |