SCHEMBL29388206

SCHEMBL29388206

N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCCCCO

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.62
▸ MEN1 O00255 2/20 0.62
▸ LMNA P02545 2/20 0.62
▸ KMT2A Q03164 2/20 0.62
▸ KDM4E B2RXH2 2/20 0.62
▸ MPO P05164 1/20 0.62
▸ TSHR P16473 1/20 0.62
▸ BLM P54132 1/20 0.62
▸ PMP22 Q01453 1/20 0.62
▸ HIF1A Q16665 1/20 0.62
▸ TACR1 P25103 2/20 0.60
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ HTR2A P28223 2/20 0.50
▸ ADRB1 P08588 1/20 0.50
▸ HTR1A P08908 1/20 0.50
▸ ADRA2A P08913 1/20 0.50
▸ SLC6A2 P23975 1/20 0.50
▸ HTR1D P28221 1/20 0.50
▸ HTR1B P28222 1/20 0.50
▸ HTR2C P28335 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25752641 1.00 MAPT (0.62) MAPTMEN1LMNAKMT2AKDM4E
SCHEMBL5925173 0.91 MAPT (0.67) MAPTMEN1LMNAKMT2AKDM4E
SCHEMBL5925171 0.91 MAPT (0.67) MAPTMEN1LMNAKMT2AKDM4E
SCHEMBL6423830 0.89 TACR1 (0.62) MAPTMEN1LMNAKMT2AKDM4E
SCHEMBL6423829 0.89 TACR1 (0.62) MAPTMEN1LMNAKMT2AKDM4E
SCHEMBL12966393 0.89 TACR1 (0.62) MAPTMEN1LMNAKMT2AKDM4E
SCHEMBL6240394 0.88 TACR1 (0.61) MAPTMEN1LMNAKMT2AKDM4E
SCHEMBL16278133 0.88 TACR1 (0.61) MAPTMEN1LMNAKMT2AKDM4E
SCHEMBL1720662 0.88 TACR1 (0.61) MAPTMEN1LMNAKMT2AKDM4E
SCHEMBL6243285 0.88 TACR1 (0.61) MAPTMEN1LMNAKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3952912-B1 CELL-PENETRATING CONJUGATE SYSTEMS UNIV DANMARKS TEKNISKE (DK) 2025-04-23 — — EP claimed
US-20230210994-A1 CELL-PENETRATING CONJUGATE SYSTEMS DANMARKS TEKNISKE UNIVERSITET (DK) 2023-07-06 — — US claimed
EP-3952912-B1 CELL-PENETRATING CONJUGATE SYSTEMS UNIV DANMARKS TEKNISKE (DK) 2025-04-23 — — EP disclosed
US-20230210994-A1 CELL-PENETRATING CONJUGATE SYSTEMS DANMARKS TEKNISKE UNIVERSITET (DK) 2023-07-06 — — US disclosed
EP-3952912-A1 CELL-PENETRATING CONJUGATE SYSTEMS Danmarks Tekniske Universitet (DK) 2022-02-16 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210994-A1 CELL-PENETRATING CONJUGATE SYSTEMS SLC2A3, SLC2A1, SLC2A2 MAPT 2405/4885MEN1 277/4885LMNA 2988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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