Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 11/20 | 0.65 |
| ▸ | ABL1 | P00519 | 5/20 | 0.65 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.65 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.65 |
| ▸ | PRKD2 | Q9BZL6 | 3/20 | 0.65 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.65 |
| ▸ | FYN | P06241 | 2/20 | 0.65 |
| ▸ | CDK2 | P24941 | 2/20 | 0.65 |
| ▸ | CSK | P41240 | 2/20 | 0.65 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.65 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.65 |
| ▸ | PRKACA | P17612 | 1/20 | 0.65 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.65 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.65 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.65 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.65 |
| ▸ | HCK | P08631 | 1/20 | 0.65 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12436039 | 1.00 | SRC (0.65) | SRCABL1PRKD3PRKD1PRKD2 | |
| SCHEMBL13019719 | 0.86 | SRC (0.71) | SRCABL1PRKD3PRKD1PRKD2 | |
| SCHEMBL29388038 | 0.83 | SRC (0.64) | SRCABL1PRKD3PRKD1PRKD2 | |
| SCHEMBL14574636 | 0.83 | SRC (0.64) | SRCABL1PRKD3PRKD1PRKD2 | |
| SCHEMBL13019725 | 0.83 | SRC (0.64) | SRCABL1PRKD3PRKD1PRKD2 | |
| SCHEMBL13019723 | 0.83 | SRC (0.73) | SRCABL1PRKD3PRKD1PRKD2 | |
| SCHEMBL29390815 | 0.83 | SRC (0.64) | SRCABL1PRKD3PRKD1PRKD2 | |
| SCHEMBL12436045 | 0.83 | SRC (0.58) | SRCABL1PRKD3PRKD1PRKD2 | |
| SCHEMBL29390904 | 0.83 | SRC (0.58) | SRCABL1PRKD3PRKD1PRKD2 | |
| SCHEMBL12436036 | 0.83 | SRC (0.62) | SRCABL1PRKD3PRKD1PRKD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11247972-B2 | Compositions and methods for treating toxoplasmosis, cryptosporidiosis, and other apicomplexan protozoan related diseases | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2022-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11247972-B2 | Compositions and methods for treating toxoplasmosis, cryptosporidiosis, and other apicomplexan protozoan related diseases | PNCK, TXK, CILK1 | SRC 132/4885ABL1 1181/4885PRKD3 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.