Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29467603 | 1.00 | SYK (0.51) | SYKCAPN1CAPN2MAPTCTSL | |
| SCHEMBL31720396 | 1.00 | SYK (0.51) | SYKCAPN1CAPN2MAPTCTSL | |
| SCHEMBL23451373 | 0.97 | SYK (0.54) | SYKCAPN1CAPN2MAPTCTSL | |
| SCHEMBL23451372 | 0.97 | SYK (0.54) | SYKCAPN1CAPN2MAPTCTSL | |
| SCHEMBL29467638 | 0.88 | SMN1; SMN2 (0.47) | SYKCAPN1CAPN2MAPTCTSL | |
| SCHEMBL29548496 | 0.88 | SMN1; SMN2 (0.47) | SYKCAPN1CAPN2MAPTCTSL | |
| SCHEMBL30407162 | 0.88 | SMN1; SMN2 (0.47) | SYKCAPN1CAPN2MAPTCTSL | |
| SCHEMBL20529378 | 0.87 | CAPN1 (0.54) | SYKCAPN1CAPN2MAPTCTSL | |
| SCHEMBL29467718 | 0.85 | CAPN1 (0.47) | SYKCAPN1CAPN2MAPTCTSL | |
| SCHEMBL16975020 | 0.84 | HTT (0.68) | SYKMAPTHTTFOLH1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986463-A1 | A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS | Hangzhou Dac Biotech Co., Ltd. (CN) | 2022-04-27 | — | — | EP | disclosed |
| CN-114040779-A | Conjugates of cell binding molecules containing branched linkers and cytotoxic agents | 杭州多禧生物科技有限公司 | 2022-02-11 | — | — | CN | disclosed |