Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 15/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2938755 | 0.95 | IGF1R (0.46) | IGF1RPPARGPPARDPPARATAS2R8 | |
| SCHEMBL2938285 | 0.89 | IGF1R (0.48) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL2942884 | 0.89 | IGF1R (0.50) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL2934260 | 0.89 | IGF1R (0.50) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL2942384 | 0.89 | IGF1R (0.50) | IGF1RPPARGPPARDPPARATAS2R8 | |
| SCHEMBL2941310 | 0.89 | IGF1R (0.50) | IGF1RPPARGPPARDPPARATAS2R8 | |
| SCHEMBL2937804 | 0.88 | IGF1R (0.52) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL2943407 | 0.88 | IGF1R (0.49) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL2938005 | 0.87 | IGF1R (0.47) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL2942365 | 0.87 | IGF1R (0.48) | IGF1RPPARGPPARDPPARATAS2R8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-B1 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2010-09-22 | — | — | EP | claimed |
| EP-1599464-B1 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2010-09-22 | — | — | EP | disclosed |
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |