Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | GNPAT | O15228 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1711315 | 0.95 | FOLH1 (0.54) | FOLH1DPP4DPP8DPP9DPP7 | |
| SCHEMBL29358709 | 0.95 | FOLH1 (0.54) | FOLH1DPP4DPP8DPP9DPP7 | |
| SCHEMBL29358689 | 0.95 | FOLH1 (0.54) | FOLH1DPP4DPP8DPP9DPP7 | |
| SCHEMBL29357446 | 0.95 | FOLH1 (0.54) | FOLH1DPP4DPP8DPP9DPP7 | |
| SCHEMBL1711313 | 0.95 | FOLH1 (0.54) | FOLH1DPP4DPP8DPP9DPP7 | |
| SCHEMBL29782763 | 0.92 | FOLH1 (0.51) | FOLH1DPP4DPP8DPP9DPP7 | |
| SCHEMBL16862515 | 0.90 | FOLH1 (0.49) | FOLH1DPP4DPP8DPP9DPP7 | |
| SCHEMBL16862514 | 0.90 | FOLH1 (0.49) | FOLH1DPP4DPP8DPP9DPP7 | |
| SCHEMBL30578949 | 0.88 | FOLH1 (0.48) | FOLH1DPP4DPP8DPP9DPP7 | |
| SCHEMBL30093154 | 0.88 | FOLH1 (0.48) | FOLH1DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022199237-A1 | MODIFIED AMINO ACIDS AND APPLICATION THEREOF IN ADC | 联宁（苏州）生物制药有限公司 | 2022-09-29 | — | — | WO | claimed |
| CN-114106088-A | Bromomethylpyrazine-based drug conjugates and ADCs | 联宁（苏州）生物制药有限公司 | 2022-03-01 | — | — | CN | claimed |
| CN-113816990-B | Modified amino acids and their use in ADCs | 联宁（苏州）生物制药有限公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022199237-A1 | MODIFIED AMINO ACIDS AND APPLICATION THEREOF IN ADC | 联宁（苏州）生物制药有限公司 | 2022-09-29 | — | — | WO | disclosed |
| CN-114106088-A | Bromomethylpyrazine-based drug conjugates and ADCs | 联宁（苏州）生物制药有限公司 | 2022-03-01 | — | — | CN | disclosed |