Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 19/20 | 0.93 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2931286 | 0.96 | IGF1R (1.00) | IGF1RPPARGPPARDPPARA | |
| Trifluoroacetic Acid SCHEMBL2940749 | 0.95 | IGF1R (0.84) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL2939949 | 0.91 | IGF1R (0.86) | IGF1RPPARGPPARDPPARA | |
| Trifluoroacetic Acid SCHEMBL2941146 | 0.90 | IGF1R (0.89) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL2941359 | 0.89 | IGF1R (0.86) | IGF1R | |
| Trifluoroacetic Acid SCHEMBL3727586 | 0.88 | IGF1R (0.72) | IGF1RPPARGPPARDPPARA | |
| Trifluoroacetic Acid SCHEMBL3730605 | 0.87 | IGF1R (0.71) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL2940541 | 0.87 | IGF1R (1.00) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL2939862 | 0.87 | IGF1R (0.82) | IGF1RPPARGPPARDPPARA | |
| Trifluoroacetic Acid SCHEMBL3732144 | 0.86 | IGF1R (0.70) | IGF1RPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-B1 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2010-09-22 | — | — | EP | claimed |